Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Feb 28:5:26.
doi: 10.3389/fped.2017.00026. eCollection 2017.

Treatment of Venous Thromboembolism in Pediatric Patients

Affiliations
Review

Treatment of Venous Thromboembolism in Pediatric Patients

Lynn Malec et al. Front Pediatr. .

Abstract

Given the increased incidence of venous thromboembolism (VTE) in pediatric patients, which has been associated with increased survival of medically complex patients and increased use of invasive supportive measures, it is important to understand treatment options and unique aspects of anticoagulant use in children. The objective of this mini-review is to outline the goals of treatment, treatment options, and adverse events associated with the use of anticoagulants in pediatric patients with VTE.

Keywords: anticoagulants; pediatrics; thromboembolism; treatment; venous thrombosis.

PubMed Disclaimer

References

    1. Raffini L, Huang YS, Witmer C, Feudtner C. Dramatic increase in venous thromboembolism in children’s hospitals in the United States from 2001 to 2007. Pediatrics (2009) 124:1001–8.10.1542/peds.2009-0768 - DOI - PubMed
    1. Monagle P, Chan AK, Goldenberg N, Ichord R, Journeycake J, Nowak-Gottl U, et al. Antithrombotic therapy in neonates and children: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guildelines. Chest (2012) 141(2 Suppl):e737S–e801S.10.1378/chest.11-2308 - DOI - PMC - PubMed
    1. Monagle P, Adams M, Mahoney M, Ali K, Barnard D, Bernstein M, et al. Outcome of pediatric thromboembolic disease: a report from the Canadian Childhood Thrombophilia Registry. Pediatr Res (2000) 47:763–6.10.1203/00006450-200006000-00013 - DOI - PubMed
    1. Goldenberg NA, Abshire T, Blatchford PJ, Fenton LZ, Halperin JL, Hiatt WR, et al. Multicenter randomized controlled trial on duration of therapy for thrombosis in children and young adults (the Kids-DOTT trial): pilot/feasibility phase findings. J Thromb Haemost (2015) 13(9):1597–1605.10.1111/jth.13038 - DOI - PMC - PubMed
    1. Monagle P, Barnes C, Ignjatovic V, Furmedge J, Newall F, Chan A, et al. Developmental haemostasis. Impact for clinical haemostasis laboratories. Thromb Haemost (2006) 95(2):362–72.10.1160/TH05-01-0047 - DOI - PubMed

LinkOut - more resources