Nutrients and the Pancreas: An Epigenetic Perspective
- PMID: 28294968
- PMCID: PMC5372946
- DOI: 10.3390/nu9030283
Nutrients and the Pancreas: An Epigenetic Perspective
Abstract
Pancreatic cancer is the fourth most common cause of cancer-related deaths with a dismal average five-year survival rate of six percent. Substitutional progress has been made in understanding how pancreatic cancer develops and progresses. Evidence is mounting which demonstrates that diet and nutrition are key factors in carcinogenesis. In particular, diets low in folate and high in fruits, vegetables, red/processed meat, and saturated fat have been identified as pancreatic cancer risk factors with a proposed mechanism involving epigenetic modifications or gene regulation. We review the current literature assessing the correlation between diet, epigenetics, and pancreatic cancer.
Keywords: epigenetics; nutrition; pancreatic cancer.
Conflict of interest statement
The authors declare no conflict of interest.
References
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- The Sol Goldman Pancreatic Cancer Research Center What Is the Pancreas? [(accessed on 5 October 2016)]. Available online: http://pathology.jhu.edu/pc/BasicOverview1.php?area=ba.
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