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. 1987 Oct;31(10):1640-1.
doi: 10.1128/AAC.31.10.1640.

Norfloxacin resistance in a clinical isolate of Escherichia coli

H Aoyama  1 , K Sato, T Kato, K Hirai, S Mitsuhashi
Affiliations

Norfloxacin resistance in a clinical isolate of Escherichia coli

H Aoyama et al. Antimicrob Agents Chemother. 1987 Oct.

Abstract

Analysis of DNA gyrase supercoiling and of norfloxacin uptake in Escherichia coli GN14176, a moderately norfloxacin-resistant clinical isolate, indicated that resistance was associated with both an altered drug target and a reduction in drug uptake.

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References

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