Interplay between Endothelial Cell Cytoskeletal Rigidity and Plasma Membrane Fluidity

Affiliations

¹ Department of Chemistry, Michigan State University, East Lansing, Michigan. Electronic address: blanchard@chemistry.msu.edu.
² Department of Physiology, Michigan State University, East Lansing, Michigan.

Comment

Gary J Blanchard et al. Biophys J. 2017.

. 2017 Mar 14;112(5):831-833.

doi: 10.1016/j.bpj.2017.01.013.

¹ Department of Chemistry, Michigan State University, East Lansing, Michigan. Electronic address: blanchard@chemistry.msu.edu.
² Department of Physiology, Michigan State University, East Lansing, Michigan.

No abstract available

Figures

Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids.
Ayee MAA, LeMaster E, Shentu TP, Singh DK, Barbera N, Soni D, Tiruppathi C, Subbaiah PV, Berdyshev E, Bronova I, Cho M, Akpa BS, Levitan I. Ayee MAA, et al. Biophys J. 2017 Jan 24;112(2):325-338. doi: 10.1016/j.bpj.2016.12.002. Biophys J. 2017. PMID: 28122218 Free PMC article.

1. Byfield F.J., Aranda-Espinoza H., Levitan I. Cholesterol depletion increases membrane stiffness of aortic endothelial cells. Biophys. J. 2004;87:3336–3343. - PMC - PubMed
1. Sun M., Northup N., Forgacs G. The effect of cellular cholesterol on membrane-cytoskeleton adhesion. J. Cell Sci. 2007;120:2223–2231. - PubMed
1. Ayee M.A., Levitan I. Paradoxical impact of cholesterol on lipid packing and cell stiffness. Front. Biosci. (Landmark Ed.) 2016;21:1245–1259. - PubMed
1. Zidovetzki R., Levitan I. Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies. Biochim. Biophys. Acta. 2007;1768:1311–1324. - PMC - PubMed
1. Chakravarthy H., Navitskaya S., Busik J.V. Role of acid sphingomyelinase in shifting the balance between proinflammatory and reparative bone marrow cells in diabetic retinopathy. Stem Cells. 2016;34:972–983. - PMC - PubMed