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Review
. 2017 Mar 15;9(381):eaaf6169.
doi: 10.1126/scitranslmed.aaf6169.

Total-body imaging: Transforming the role of positron emission tomography

Simon R Cherry  1 , Ramsey D Badawi  2 , Joel S Karp  3 , William W Moses  4 , Pat Price  5 , Terry Jones  2
Affiliations
Review

Total-body imaging: Transforming the role of positron emission tomography

Simon R Cherry et al. Sci Transl Med. .

Abstract

The first total-body positron emission tomography (TB-PET) scanner represents a radical change for experimental medicine and diagnostic health care.

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Figures

Fig. 1
Fig. 1. Seeing into our future
Illustration depicting (A) a conventional PET scanner and (B) total-body PET (TB-PET) scanner. An x-ray computed tomography (CT) scanner will be mounted on the front of the TB-PET gantry for anatomical coregistration to ensure optimal integration of anatomical imaging with molecular imaging.
See this image and copyright information in PMC

References

    1. Bailey DL, Townsend DW, Valk PE, Maisey MN, editors. Positron Emission Tomography Basic Sciences. Springer; 2005.
    1. Cherry SR, Karp J, Moses WW, Qi J, Bec J, Berg E, Choong WS, Huber J, Krishnamoorthy S, Peng Q, Poon J, Surti S, Zhang X, Zhou J, Jones T, Badawi R. EXPLORER: An ultra-sensitive total-body PET scanner for biomedical research. Proceedings of the IEEE Medical Imaging Conference; Seoul, Korea. 27 October to 2 November 2013; www.nss-mic.org/2013/program/ListProgramDB.asp?session=M03.
    1. Badawi RD, Poon JK, Zhang X, Karp JS, Moses WW, Qi J, Graham MM, Mankoff DA, Wahl RL, Jagust WJ, Budinger TF, Jones T, Cherry SR. EXPLORER: An ultrasensitive total-body PET scanner: Application feasibility simulations. Proceedings of the World Molecular Imaging Congress; Savannah, GA,. 18 to 21 September 2013; www.wmis.org/abstracts/2013/data/papers/LBAP125.htm.
    1. Poon JK, Dahlbom ML, Moses WW, Balakrishnan K, Wang W, Cherry SR, Badawi RD. Optimal whole-body PET scanner configurations for different volumes of LSO scintillator: A simulation study. Phys Med Biol. 2012;57:4077–4094. - PMC - PubMed
    1. National Institutes of Health (NIH) Common Fund, NIH Director's Transformative Research Award. http://commonfund.nih.gov/TRA/.

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