Modeling Alzheimer's disease in mice with human neurons
- PMID: 28298426
- DOI: 10.1126/scitranslmed.aam9867
Modeling Alzheimer's disease in mice with human neurons
Abstract
Human neurons transplanted into a mouse model for Alzheimer's disease show human-specific vulnerability to β-amyloid plaques and may help to identify new therapeutic targets.
Copyright © 2017, American Association for the Advancement of Science.
Comment on
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Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.Neuron. 2017 Mar 8;93(5):1066-1081.e8. doi: 10.1016/j.neuron.2017.02.001. Epub 2017 Feb 23. Neuron. 2017. PMID: 28238547
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