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. 2017 Jan-Mar;20(1):59-61.
doi: 10.4103/0972-2327.192386.

Labrune syndrome: A unique leukoencephalopathy

Leena Pahuja  1 , Elisheba Patras  1 , Sachin Sureshbabu  2 , Nittin Parkhe  1 , Laxmi Khanna  2
Affiliations

Labrune syndrome: A unique leukoencephalopathy

Leena Pahuja et al. Ann Indian Acad Neurol. 2017 Jan-Mar.
No abstract available

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Computed tomography topogram revealed luckenschadel skull with intracranial calcification. (b) Non contrast axial computed tomography image showing calcification of the Dentate nuclei. (c) Non contrast axial computed tomography images showing exuberant calcification in bilateral Gangliocapsular region, Thalamus (red arrows) and (d) grey-white matter junction
Figure 2
Figure 2
T2-weighted (a and b) and corresponding fluid-attenuated inversion recovery (c and d) images showing diffuse white matter hyperintensity suggesting leukoencephalopathy
Figure 3
Figure 3
T1-weighted (a and b) and corresponding T2-weighted (c and d) images showing cysts in bilateral Cerebellar hemispheres (white arrow), above the third ventricle and in the region of Pineal gland. There is also associated obstructive hydrocephalus
Figure 4
Figure 4
(a and b) magnetic resonance imaging shows blooming in bilateral Basal Ganglia, Thalami and Dentate nuclei on gradient echo images suggesting calcification
See this image and copyright information in PMC

References

    1. Labrune P, Lacroix C, Goutières F, de Laveaucoupet J, Chevalier P, Zerah M, et al. Extensive brain calcifications, leukodystrophy, and formation of parenchymal cysts: A new progressive disorder due to diffuse cerebral microangiopathy. Neurology. 1996;46:1297–301. - PubMed
    1. Nagae-Poetscher LM, Bibat G, Philippart M, Rosemberg S, Fatemi A, Lacerda MT, et al. Leukoencephalopathy, cerebral calcifications, and cysts: New observations. Neurology. 2004;62:1206–9. - PubMed
    1. Turkulov V, Madle-Samardzija N, Canak G, Vukadinov J, Aleksic-Dordevic M. Clinical and diagnostic approaches to neurocysticercosis. Med Pregl. 2001;54:353–6. - PubMed
    1. Caldemeyer KS, Mathews VP, Edwards-Brown MK, Smith RR. Central nervous system cryptococcosis: Parenchymal calcification and large gelatinous pseudocysts. AJNR Am J Neuroradiol. 1997;18:107–9. - PMC - PubMed
    1. Corboy JR, Gault J, Kleinschmidt-DeMasters BK. An adult case of leukoencephalopathy with intracranial calcifications and cysts. Neurology. 2006;67:1890–2. - PubMed