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Review
. 2017:2017:3978595.
doi: 10.1155/2017/3978595. Epub 2017 Feb 16.

Therapeutic Potential of Olfactory Ensheathing Cells and Mesenchymal Stem Cells in Spinal Cord Injuries

Zadroga Anna  1 , Jezierska-Woźniak Katarzyna  2 , Czarzasta Joanna  1 , Monika Barczewska  2 , Wojtkiewicz Joanna  3 , Maksymowicz Wojciech  2
Affiliations
Review

Therapeutic Potential of Olfactory Ensheathing Cells and Mesenchymal Stem Cells in Spinal Cord Injuries

Zadroga Anna et al. Stem Cells Int. 2017.

Erratum in

Abstract

Spinal cord injury (SCI) is a devastating neurological condition that affects individuals worldwide, significantly reducing quality of life, for both patients and their families. In recent years there has been a growing interest in cell therapy potential in the context of spinal cord injuries. The present review aims to discuss and compare the restorative approaches based on the current knowledge, available spinal cord restorative cell therapies, and use of selected cell types. However, treatment options for spinal cord injury are limited, but rehabilitation and experimental technologies have been found to help maintain or improve remaining nerve function in some cases. Mesenchymal stem cells as well as olfactory ensheathing cells seem to show therapeutic impact on damaged spinal cord and might be useful in neuroregeneration. Recent research in animal models and first human trials give patients with spinal cord injuries hope for recovery.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Scheme: therapy of stem cells.
Figure 2
Figure 2
Classification of cells with regenerative potential.
See this image and copyright information in PMC

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