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. 2016 Oct-Dec;12(4 Suppl):17.
doi: 10.14797/mdcj-12-4s1-17.

Lung Volume Reduction Coils as a Novel Bronchoscopic Treatment for Emphysema

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Lung Volume Reduction Coils as a Novel Bronchoscopic Treatment for Emphysema

Timothy A Connolly. Methodist Debakey Cardiovasc J. 2016 Oct-Dec.

Abstract

Chronic obstructive pulmonary disease remains a major cause of morbidity and mortality worldwide. Despite regular advances in pharmacology, there remains great potential for addressing structural deficiencies, especially in emphysema. The loss of alveolar attachments to small bronchial tubes results in diffuse loss of elastic recoil and airway collapse during exhalation. This appears physiologically as hyperinflation of lung volumes with flattened diaphragms and significantly elevated residual volumes (RV) on pulmonary function testing (predicted RV > 175%).

Keywords: COPD; chronic obstructive pulmonary disease; emphysema; lung volume reduction coils; nitinol coils.

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