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. 2017 Jan-Mar;12(1):65-80.
doi: 10.4103/jovr.jovr_253_16.

Clinical Practice Guidelines for Prevention, Diagnosis and Management of Early and Delayed-onset Ocular Injuries Due to Mustard Gas Exposure

Zhale Rajavi  1 , Sare Safi  2 , Mohammad Ali Javadi  2 , Mohammad Reza Jafarinasab  1 , Sepehr Feizi  3 , Mohammadreza Sedighi Moghadam  4 , Khosrow Jadidi  5 , Mahmoud Babaei  5 , Armin Shirvani  6 , Alireza Baradaran-Rafii  7 , Hossein Mohammad-Rabei  8 , Hossein Ziaei  1 , Mohammad Ghassemi-Broumand  9 , Siamak Delfaza Baher  8 , Mostafa Naderi  5 , Mahmoodreza Panahi-Bazaz  10 , Siamak Zarei-Ghanavati  11 , Shahriar Hanjani  12 , Hassan Ghasemi  13 , Ramin Salouti  14 , Mojgan Pakbin  2 , Bahareh Kheiri  2
Affiliations

Clinical Practice Guidelines for Prevention, Diagnosis and Management of Early and Delayed-onset Ocular Injuries Due to Mustard Gas Exposure

Zhale Rajavi et al. J Ophthalmic Vis Res. 2017 Jan-Mar.

Erratum in

Abstract

Purpose: To develop clinical practice guidelines (CPGs) for prevention, diagnosis, treatment and follow-up of ocular injuries caused by exposure to mustard gas.

Methods: The clinical questions were designed by the guideline team. Websites and databases including National Guidelines Clearinghouse, National Institute for Clinical Excellence, Cochrane, and PubMed were searched to find related CPGs and explore possible answers to the clinical questions. Since there were no relevant CPGs in the literature, related articles in Persian and English languages were extracted. Each article along with its level of evidence was summarized. Additionally, hand search was performed by looking the reference list of each article. Consequently, recommendations were developed considering the clinical benefits and side effects of each therapeutic modality. The recommendations were re-evaluated in terms of customization criteria. All recommendations along with the related evidence were scored from 1 to 9 by experts from all medical universities of Iran. The level of agreement among the experts was evaluated by analyzing the given scores.

Results: The agreement was achieved for all recommendations. The experts suggested a number of minor modifications which were applied to the recommendations. Finally, CPGs were developed with 98 recommendations under three major domains including prevention of injury, diagnosis and management of the acute and delayed-onset mustard gas ocular injuries.

Conclusion: Considering the lack of CPGs for the prevention, diagnosis, and management of mustard gas-induced keratitis, these recommendations would be useful to prevent the serious ocular complications of mustard gas and standardize eye care services to the affected individuals.

Keywords: Clinical Practice Guidelines; Eye Injury; Iran; Mustard Gas.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Ocular injuries due to mustard gas exposure in acute phase. Reproduced from “Javadi MA, Feizi S. Mustard gas ocular injuries in chemical warfare victims. 1st ed. Tehran: FARHANG FARDA; 2014”.
Figure 2
Figure 2
Chronic and delayed--onset ocular injuries due to mustard gas exposure. Reproduced from “Javadi MA, Feizi S. Mustard gas ocular injuries in chemical warfare victims. 1st ed. Tehran: FARHANG FARDA; 2014”.
See this image and copyright information in PMC

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