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Review
. 2017 Feb 23:6:180.
doi: 10.12688/f1000research.10094.1. eCollection 2017.

Understanding the role of serotonin in psychiatric diseases

Donatella Marazziti  1
Affiliations
Review

Understanding the role of serotonin in psychiatric diseases

Donatella Marazziti. F1000Res. .

Abstract

Serotonin (5-HT) continues to attract researchers' interest after almost a century. However, despite these efforts, its role has not yet been fully elucidated. It is now evident that 5-HT does not modulate single functions but rather a multiplicity of activities and behaviors present in both normal and several pathological conditions in a less deterministic way than previously assumed. This article aims to briefly review some of the latest advancements in the general role of 5-HT in psychiatry, particularly in depression, and offer the author's personal reflections.

Keywords: depression; pathophysiology; psychiatric disorders; serotonin.

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Conflict of interest statement

Competing interests: The author declares that she has no competing interests.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

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