Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Feb 24;114(7):130-136.
doi: 10.3238/arztebl.2017.0130.

Lower Limb Amputation in Germany

Affiliations

Lower Limb Amputation in Germany

Knut Kröger et al. Dtsch Arztebl Int. .

Abstract

Background: Declining amputation rates have been reported in multiple countries in recent years. It is not yet known whether amputation rates have declined in Germany as well.

Methods: On the basis of DRG (diagnosis-related group) data, we received a list from the German Federal Statistical Office of all major and minor amputations documented in German hospitals from 2005 to 2014. Changes over this period were studied with linear regression.

Results: The absolute number of amputations per year in Germany rose slightly from 55 689 in 2005 to 57 637 (+3.5%) in 2014. After the exclusion of cases in which the main diagnosis was trauma, intoxication, musculoskeletal disease, diseases of the skin and subcutaneous tissue, or neoplasia, the corresponding numbers were 48 043 in 2005 and 48 561 in 2014 (+1.1%). The age-adjusted rate of major amputations per 100 000 persons per year fell from 23.3 to 16.1 (-30.9%), while the rate of minor amputations rose from 35.0 to 43.9 (+25.4%). The percentage of major amputations that took place in patients with diabetes mellitus as the main diagnosis or a side diagnosis declined from 70.2% to 63.7%. For all of these changes, p <0.0001.

Conclusion: From 2005 to 2014, the major amputation rate fell by 30.9% while the minor amputation rate rose by 25.4%. The goal of lowering amputation rates still further will be best served not only by applying the recognized preventive measures in patients with foot lesions, but also by further research into the causes of the recent changes in amputation numbers. Prospective registries will be needed.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Age-standardized rates of all major and minor amputations per 100 000 inhabitants and all major and minor amputations after exclusion of cases with the ICD main diagnoses C00–D48, L00–L99, M00–M99, and SOO–T98 (CLMS)
Figure 2
Figure 2
Proportion of all major and minor amputations with diabetes mellitus (E10–E14) coded as main or secondary diagnosis, after exclusion of cases with the ICD main diagnoses C00–D48, L00–L99, M00–M99, and SOO–T98 (CLMS)
eFigure
eFigure
Rate of major and minor amputations per 100 000 from the fourth decade of life onward for the years 2005 and 2014 after exclusion of cases with the ICD main diagnoses C00–D48, L00–L99, M00–M99, and SOO–T98 (CLMS) (top, men; bottom, women); ICD, International Classification of Diseases and Related Health Problems

Comment in

References

    1. The Saint Vincent Declaration on diabetes care and research in Europe. Acta Diabetol. 1989;(10):143–144.
    1. Nickolaus B. Diabetes mellitus - Gutachten identifiziert Mängel. Dtsch Arzteblatt. 2012;109
    1. Goodney PP, Beck AW, Nagle J, Welch HG, Zwolak RM. National trends in lower extremity bypass surgery, endovascular interventions, and major amputations. J Vasc Surg. 2009;50:54–60. - PubMed
    1. Rowe VL, Lee W, Weaver FA, Etzioni D. Patterns of treatment for peripheral arterial disease in the United States: 1996-2005. J Vasc Surg. 2009;49:910–917. - PubMed
    1. Li Y, Burrows NR, Gregg EW, Albright A, Geiss LS. Declining rates of hospitalization for nontraumatic lower-extremity amputation in the diabetic population aged 40 years or older: US., 1988-2008. Diabetes Care. 2012;35:273–277. - PMC - PubMed