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. 2017 Mar 17;355(6330):1129-1130.
doi: 10.1126/science.aan0662. Epub 2017 Mar 16.

Developing an HIV vaccine

Barton F Haynes  1 , Dennis R Burton  2   3
Affiliations

Developing an HIV vaccine

Barton F Haynes et al. Science. .
No abstract available

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Figures

Figure
Figure. The HIV envelope trimer
The structure of a recombinant trimer has been shown to closely resemble that of the membrane-associated molecule. The trimer is the sole target of bnAbs, and most bnAbs either bind to or accommodate glycans.
See this image and copyright information in PMC

References

    1. Corey L, et al. Sci Transl Med. 2015;7:310. - PMC - PubMed
    1. Burton DR, Mascola J. Nat Immunol. 2015;16:571. - PMC - PubMed
    1. Stephenson KE, et al. Curr Opin Immunol. 2016;41:39. - PMC - PubMed
    1. Hansen SG, et al. Science. 2013;340:1237874. - PMC - PubMed
    1. Burton DR, Hangartner L. Ann Rev Immunol. 2016;34:635. - PMC - PubMed

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