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. 2017 Jan-Mar;35(1):129-133.
doi: 10.4103/ijmm.IJMM_16_12.

Trends in spoligotype patterns of Mycobacterium tuberculosis strains in central India

Prabha Desikan  1 , Devendra S Chauhan  2 , Nikita Panwalkar  1 , Pragya Sharma  2 , Priyanka Yadav  2
Affiliations
Free article

Trends in spoligotype patterns of Mycobacterium tuberculosis strains in central India

Prabha Desikan et al. Indian J Med Microbiol. 2017 Jan-Mar.
Free article

Abstract

This study aims to understand trends in spoligotype patterns of Mycobacterium tuberculosis (MTB) in Central India. Elucidation of these trends may provide baseline information to understand the transmission dynamics of strains of MTB in the region. Spoligotyping was carried out on 340 MTB strains isolated from clinical samples received from 2007 to 2011. The prevalence of ST26/CAS1_Del, ST11/EAI3_IND, ST288/CAS2, ST25/CAS1_Del and Beijing lineages showed waxing and waning trends. ST26/CAS1_Del and ST11/EAI3_IND lineages were consistently present and were predominant. Well-established lineages showed a consistent presence in the community. New orphan lineages appeared to be less capable of establishing themselves.

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