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Comparative Study
. 1987 Dec;7(12):4589-93.
doi: 10.1128/mcb.7.12.4589-4593.1987.

Molecular analysis of G+C-rich upstream sequences regulating transcription of the human carbonic anhydrase II gene

L H Shapiro  1 , P J Venta, R E Tashian
Affiliations
Comparative Study

Molecular analysis of G+C-rich upstream sequences regulating transcription of the human carbonic anhydrase II gene

L H Shapiro et al. Mol Cell Biol. 1987 Dec.

Abstract

The upstream promoter sequences of the human carbonic anhydrase II (CA II) gene have been studied by 5' deletion analysis. Promoter activity was assayed by transfection and chloramphenicol acetyltransferase assay in both human HeLa cells and murine L cells. This investigation showed that the CA II promoter is comparable in activity to that of the simian virus 40 early-region promoter and enhancer and that the CA II upstream sequences exert a different pattern of control in the two cell lines.

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References

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