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. 1984 Jul;193(4):252-256.
doi: 10.1007/BF01260347.

Ecdysteroids induce morphological changes in continuous cell lines of Lepidoptera

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Ecdysteroids induce morphological changes in continuous cell lines of Lepidoptera

Naomi Kislev et al. Wilehm Roux Arch Dev Biol. 1984 Jul.

Abstract

In the continuous cell lines of the LepidopteraTrichoplusia ni (TN-368) andSpodoptera littoralis (HPB-SL-26), ecdysone and 20-hydroxyecdysone cause a series of morphological changes: some cells aggregate, elongate and extend long thin processes. The extent and rapidity of changes are dose dependent, 20-hydroxy-ecdysone being much more active then ecdysone. The continuous cell lines ofS. littoralis (UIV-SL-573) andS. frugiperda (IPLB-SF-21) were much less responsive to the presence of the ecdysteroids.

Keywords: Ecdysteroids; Lepidoptera cell lines; Morphological changes.

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