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. 1981 Jul;190(4):197-207.
doi: 10.1007/BF00848303.

Tissue specific nuclear antigens in the germinal vesicle ofXenopus laevis oocytes

Christine Dreyer  1 , Helen Singer  1 , Peter Hausen  1 , Ursula Müller  1 , Elisabeth Siegel  1
Affiliations

Tissue specific nuclear antigens in the germinal vesicle ofXenopus laevis oocytes

Christine Dreyer et al. Wilehm Roux Arch Dev Biol. 1981 Jul.

Abstract

A library of hybridoma cell lines has been established which produce monoclonal antibodies against antigens from the germinal vesicle ofXenopus laevis oocytes. Many of the antigens are also found in the nuclei ofXenopus embryonic cells in culture. The fate of two of these antigens during embryogenesis was traced by immunofluorescence on embryo and tadpole sections. Early in development these antigens appear to be evenly distributed in the nuclei of all cells. In later stages they gradually disappear from most embryonic structures but are strongly accumulated in the nuclei of some specific cell types and organs.

Keywords: Embryogenesis; Monoclonal antibodies; Oocyte nuclear proteins.

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