Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Mar 16;65(6):961-962.
doi: 10.1016/j.molcel.2017.02.029.

Redox Control of Mitochondrial Calcium Uptake

Nicolas Demaurex  1 , Manon Rosselin  2
Affiliations
Free article

Redox Control of Mitochondrial Calcium Uptake

Nicolas Demaurex et al. Mol Cell. .
Free article

Abstract

Dong et al. (2017) establish how the mitochondrial Ca2+ uniporter (MCU) integrates Ca2+ and oxidative stress signals by identifying a cysteine residue that controls MCU channel activity, a mechanism causing mitochondrial Ca2+ overload and cell death during oxidative stress.

Keywords: apoptosis; cell signaling; inflammation; ion channels; metabolism; mitochondria; oxidative stress.

PubMed Disclaimer

LinkOut - more resources