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Comparative Study
. 1987 Dec;6(6):682-4.
doi: 10.1007/BF02013071.

Comparative activity of LY146032 against anaerobic cocci

D Greenwood  1 , J Palfreyman
Affiliations
Comparative Study

Comparative activity of LY146032 against anaerobic cocci

D Greenwood et al. Eur J Clin Microbiol. 1987 Dec.

Abstract

Fifty strains of anaerobic gram-positive cocci were tested in vitro against benzylpenicillin, teicoplanin, vancomycin and LY146032. The organisms displayed a wide range of susceptibility to penicillin and the minimum inhibitory concentration for 11 of the strains was greater than or equal to 1 mg penicillin/L. The activity of teicoplanin exceeded that of vancomycin by a factor of two. The activity of LY 146032 varied in different culture media and was dramatically potentiated by the addition of a physiological concentration of calcium. Peptococci were, in general, more susceptible than peptostreptococci to penicillin and to LY146032 in the absence of added calcium.

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References

    1. Antimicrob Agents Chemother. 1978 Sep;14(3):371-6 - PubMed
    1. Eur J Clin Microbiol. 1987 Feb;6(1):84-90 - PubMed
    1. J Antimicrob Chemother. 1987 Aug;20(2):213-21 - PubMed
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