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A proposal for standardized grading of chronic changes in native kidney biopsy specimens

Sanjeev Sethi et al. Kidney Int. 2017 Apr.
Free article

Abstract

Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis, and we report these findings as an overall chronicity grade.

Keywords: arteriosclerosis; glomerulosclerosis; interstitial fibrosis; native kidney biopsy; tubular atrophy.

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