Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jun;44(6):2595-2612.
doi: 10.1002/mp.12227. Epub 2017 Apr 20.

Motion management strategies and technical issues associated with stereotactic body radiotherapy of thoracic and upper abdominal tumors: A review from NRG oncology

Edward D Brandner  1 , Indrin J Chetty  2 , Tawfik G Giaddui  3 , Ying Xiao  4 , M Saiful Huq  1
Affiliations

Motion management strategies and technical issues associated with stereotactic body radiotherapy of thoracic and upper abdominal tumors: A review from NRG oncology

Edward D Brandner et al. Med Phys. 2017 Jun.

Abstract

The efficacy of stereotactic body radiotherapy (SBRT) has been well demonstrated. However, it presents unique challenges for accurate planning and delivery especially in the lungs and upper abdomen where respiratory motion can be significantly confounding accurate targeting and avoidance of normal tissues. In this paper, we review the current literature on SBRT for lung and upper abdominal tumors with particular emphasis on addressing respiratory motion and its affects. We provide recommendations on strategies to manage motion for different, patient-specific situations. Some of the recommendations will potentially be adopted to guide clinical trial protocols.

Keywords: 4D; SBRT; abdomen; gating; lung; respiratory motion; stereotactic body radiotherapy.

PubMed Disclaimer

Conflict of interest statement

The authors have no relevant conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Illustration of target volume contours: the innermost contour is the GTV, the lightest contour is the expansion of the GTV to create the IGTV, the next contour is the ITV, and the outermost contour is the PTV. [Color figure can be viewed at wileyonlinelibrary.com]
See this image and copyright information in PMC

References

    1. Onishi H, Shirato H, Nagata Y, et al. Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage I non‐small cell lung cancer: Updated results of 257 patients in a japanese multi‐institutional study. J Thorac Oncol. 2007;2:S94–S100. - PubMed
    1. Baumann P, Nyman J, Hoyer M, et al. Outcome in a prospective phase II trial of medically inoperable stage I non‐small‐cell lung cancer patients treated with stereotactic body radiotherapy. J Clin Oncol. 2009;27:3290–6. - PubMed
    1. Inoue T, Katoh N, Onimaru R, et al. Stereotactic body radiotherapy using gated radiotherapy with real‐time tumor‐tracking for stage I non‐small cell lung cancer. Radiat Oncol. 2013;8:69. - PMC - PubMed
    1. Jiang SB. Technical aspects of image‐guided respiration‐gated radiation therapy. Med Dosim. 2006;31:141–151. - PubMed
    1. Fassi A, Schaerer J, Fernandes M, Riboldi M, Sarrut D, Baroni G. Tumor tracking method based on a deformable 4D CT breathing motion model driven by an external surface surrogate. Int J Radiat Oncol Biol Phys. 2014;88:182–188. - PubMed