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Randomized Controlled Trial
. 2017 Jun 3;13(6):1-8.
doi: 10.1080/21645515.2017.1285476. Epub 2017 Feb 21.

Prenatal vaccination education intervention improves both the mothers' knowledge and children's vaccination coverage: Evidence from randomized controlled trial from eastern China

Yu Hu  1 , Yaping Chen  1 , Ying Wang  1 , Quanwei Song  1 , Qian Li  1
Affiliations
Randomized Controlled Trial

Prenatal vaccination education intervention improves both the mothers' knowledge and children's vaccination coverage: Evidence from randomized controlled trial from eastern China

Yu Hu et al. Hum Vaccin Immunother. .

Abstract

Objectives: To verify the effectiveness of prenatal vaccination education intervention on improving mother's vaccination knowledge and child's vaccination status in Zhejiang province, eastern China.

Methods: Pregnant women with ≥ 12 gestational weeks were recruited and randomly assigned into the intervention group and the control group. The intervention group were given a vaccination education session while the control group were not. Two round surveys were performed before and 3 months after the intervention. The vaccination status of child was extracted at 12 months of age from immunization information system. The differences of the vaccination knowledge, the coverage, the completeness and the timeliness of vaccination between 2 groups were evaluated. The effectiveness of vaccination education intervention was assessed, under the control of the other demographic variables.

Results: Among the 1252 participants, 851 subjects replied to the post-survey. Significant improvements of vaccination knowledge between the pre- and the post- survey in the intervention group were observed (Mean ± S.D:1.8 ± 1.1 vs. 3.7 ± 1.2 for vaccines score and 2.7 ± 1.5 vs. 4.8 ± 1.0 for vaccine policy score, respectively). The coverage of fully vaccination was significantly higher in the intervention group (90.0% vs. 82.9%, P<0.01). The timeliness of fully vaccination was significantly higher in the intervention group (51.9% vs. 33.0%, P<0.01). In the intervention group, pregnant women were more likely to be with high score of knowledge (OR = 5.2, 95%CI: 2.6-8.8), and children were more likely to complete the full series of vaccination (OR = 3.4, 95%CI: 2.1-4.8), and children were more likely to complete the full series of vaccination in a timely manner (OR = 2.3, 95%CI: 1.6-3.5).

Conclusions: Vaccination education in the pregnant women can effectively improve the knowledge regarding immunization and increase the coverage, the completeness and the timeliness of childhood vaccination. Strong partnership needs to be established between the obstetricians and the vaccination staff to improve the performance of NIP.

Keywords: Education intervention; prenatal; randomized controlled trial; vaccination; vaccination coverage.

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References

    1. Hu Y, Chen Y, Guo J, Tang X, Shen L. Completeness and timeliness of vaccination and determinants for low and late uptake among young children in eastern China. Hum Vaccin Immunother 2014; 10:1408-15; https://doi.org/10.4161/hv.28054 - DOI - PMC - PubMed
    1. Li Q, Hu Y, Zhong Y, Chen Y, Tang X, Guo J, et al.. Using the Immunization Information System to determine vaccination coverage rates among children aged 1-7 years: a report from Zhejiang Province, China. Int J Environ Res Public Health 2014; 11:2713-28; PMID: 24603495; https://doi.org/10.3390/ijerph110302713 - DOI - PMC - PubMed
    1. Davis TC, Fredrickson DD, Bocchini C, Arnold CL, Green KW, Humiston SG, et al.. Improving vaccine risk/benefit communication with an immunization education package: a pilot study. Ambul Pediatr 2002; 2:193-200; PMID: 12014979; https://doi.org/10.1367/1539-4409(2002)002<0193:IVRBCW>2.0.CO;2 - DOI - PubMed
    1. Davis TC, Fredrickson DD, Kennen EM, Arnold C, Shoup E, Sugar M, et al.. Childhood vaccine risk/benefit communication among public health clinics: a time-motion study. Public Health Nursing 2004; 21:228-36; PMID: 15144367; https://doi.org/10.1111/j.0737-1209.2004.021305.x - DOI - PubMed
    1. Zuniga de Nuncio ML, Nader PR, Sawyer MH, De Guire M, Prislin R, Elder JP. A prenatal intervention study to improve timeliness of immunization initiation in Latino infants. J Community Health 2003; 28:151-65; PMID: 12705316; https://doi.org/10.1023/A:1022651631448 - DOI - PubMed

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