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Review
. 2017 May;50(3):254-260.
doi: 10.5946/ce.2016.115. Epub 2017 Mar 21.

Clinical and Biological Features of Interval Colorectal Cancer

Yu Mi Lee  1 , Kyu Chan Huh  1
Affiliations
Review

Clinical and Biological Features of Interval Colorectal Cancer

Yu Mi Lee et al. Clin Endosc. 2017 May.

Abstract

Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs. The clinical and biological features of I-CRC should be elucidated to prevent the development of interval colon cancer.

Keywords: Colonoscopy; Interval colorectal cancers.

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Conflict of interest statement

Conflicts of Interest:The authors have no financial conflicts of interest.

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