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. 2017 Apr;23(4):715-717.
doi: 10.3201/eid2304.161872.

Treatment Failure of Dihydroartemisinin/Piperaquine for Plasmodium falciparum Malaria, Vietnam

Bui Quang Phuc, Charlotte Rasmussen, Tran Thanh Duong, Le Than Dong, Mai Anh Loi, Didier Ménard, Joel Tarning, Dorina Bustos, Pascal Ringwald, Gawrie Loku Galappaththy, Nguyen Quang Thieu

Treatment Failure of Dihydroartemisinin/Piperaquine for Plasmodium falciparum Malaria, Vietnam

Bui Quang Phuc et al. Emerg Infect Dis. 2017 Apr.

Abstract

We conducted a study in Binh Phuoc, Vietnam, in 2015 on the therapeutic efficacy of dihydroartemisinin/piperaquine for Plasmodium falciparum malaria. A high number of treatment failures (14/40) was found, and piperaquine resistance in Vietnam was confirmed. A change in the malaria treatment policy for Vietnam is in process.

Keywords: Plasmodium falciparum; Vietnam; antimicrobial resistance; artemisinin; dihydroartemisinin/piperaquine; drug resistance; malaria; mefloquine; piperaquine; vector-borne infections.

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