Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Apr;5(2):123-127.
doi: 10.1007/s13205-014-0214-0. Epub 2014 Apr 8.

Nanoemulsion: an advanced mode of drug delivery system

Manjit Jaiswal  1 , Rupesh Dudhe  2 , P K Sharma  2
Affiliations

Nanoemulsion: an advanced mode of drug delivery system

Manjit Jaiswal et al. 3 Biotech. 2015 Apr.

Abstract

An advanced mode of drug delivery system has been developed to overcome the major drawbacks associated with conventional drug delivery systems. This review gives a detailed idea about a nanoemulsion system. Nanoemulsions are nano-sized emulsions, which are manufactured for improving the delivery of active pharmaceutical ingredients. These are the thermodynamically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of an emulsifying agent, i.e., surfactant and co-surfactant. The droplet size of nanoemulsion falls typically in the range 20-200 nm. The main difference between emulsion and nanoemulsion lies in the size and shape of particles dispersed in the continuous phase. In this review, the attention is focused to give a basic idea about its formulation, method of preparation, characterization techniques, evaluation parameters, and various applications of nanoemulsion.

Keywords: Drug delivery; Emulgents; High-pressure homogenization; Nanoemulsion.

PubMed Disclaimer

References

    1. Ahuja A, Ali J, Baboota S, Faisal MS, Shakeell F, Shafiq S. Stability evaluation of Celecoxib nanoemulsion containing Tween 80. Thai J Pharm Sci. 2008;32:4–9.
    1. Alka AJA, Baboota S, Shakeel F, Shafiq S. Design development and evaluation of novel nanoemulsion formulations for transdermal potential of Celecoxib. Acta Pharm. 2007;57:315–332. - PubMed
    1. Anton N, Benoit JP, Saulnier P. Design and production of nanoparticles formulated from nano-emulsion templates-a review. J Control Release. 2008;128:185–199. doi: 10.1016/j.jconrel.2008.02.007. - DOI - PubMed
    1. Asua JM. Miniemulsion polymerization. Prog Polym Sci. 2002;27:1283–1346. doi: 10.1016/S0079-6700(02)00010-2. - DOI
    1. Banker GS, Lieberman HA, Rieger MM. Pharmaceutical dosage forms. Disperse Syst Marcel Dekker. 2002;2(3):339–340.