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Comment
. 2017 Mar 20;27(6):R223-R225.
doi: 10.1016/j.cub.2017.02.010.

Protist Evolution: Stealing Genes to Gut It Out

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Comment

Protist Evolution: Stealing Genes to Gut It Out

David Moreira et al. Curr Biol. .

Abstract

The amount and evolutionary impact of horizontal gene transfer in eukaryotes remain contentious issues. A new phylogenomic study suggests that gene transfer from prokaryotes has contributed significantly to the adaptation and metabolic evolution of Blastocystis, the most widespread human gut eukaryotic parasite.

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Figures

Figure 1
Figure 1. Horizontal gene transfers involved in nitrogen metabolism shared by Blastocystis and other eukaryotic unicellular parasites.
The metabolic diagram, based on Eme et al. [6], shows all enzymes acquired by Blastocystis from different donors. Those that are shared by several other distantly related protist parasites, the excavates Giardia and Trichomonas, the ichthyosporean Sphaeroforma, and the amoebozoan Entamoeba, are highlighted in yellow and the species where the respective enzyme is found are indicated.

Comment on

References

    1. Gast RJ, Sanders RW, Caron DA. Ecological strategies of protists and their symbiotic relationships with prokaryotic microbes. Trends Microbiol. 2009;17:563–569. - PubMed
    1. Koonin EV, Makarova KS, Aravind L. Horizontal gene transfer in prokaryotes: quantification and classification. Annu Rev Microbiol. 2001;55:709–742. - PMC - PubMed
    1. López-García P, Zivanovic Y, Deschamps P, Moreira D. Bacterial gene import and mesophilic adaptation in archaea. Nat Rev Microbiol. 2015;13:447–456. - PMC - PubMed
    1. Koonin EV. Horizontal gene transfer: essentiality and evolvability in prokaryotes, and roles in evolutionary transitions. 1000Res. 2016;5:1805. - PMC - PubMed
    1. Ku C, Martin WF. A natural barrier to lateral gene transfer from prokaryotes to eukaryotes revealed from genomes: the 70 % rule. BMC Biol. 2016;14:89. - PMC - PubMed

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