Neuroendocrine Tumors of the Stomach

Abstract

Gastric neuroendocrine tumors (NETs) are classified into three types. Type I gastric NETs are associated with chronic atrophic gastritis. They have a good prognosis and endoscopic resection is the mainstay of treatment. Type II gastric NETs are caused by hypergastrinemia. They have a poorer prognosis, and resection is required to control the disease. Endoscopic versus surgical resection is recommended for the gastric lesion. Type III gastric NETs are sporadic and not associated with any specific condition. They have the worst prognosis with the highest rate of metastatic disease, and oncologic resection is recommended. Medical therapies have some role.

Keywords: Chronic atrophic gastritis; Gastric carcinoid; Gastric neuroendocrine tumor; Sporadic carcinoid; Zollinger-Ellison syndrome.