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Editorial
. 2017 Mar 21;6(3):e005737.
doi: 10.1161/JAHA.117.005737.

Warning About Shortcuts in Drug Development

Robert M Califf  1
Affiliations
Editorial

Warning About Shortcuts in Drug Development

Robert M Califf. J Am Heart Assoc. .
No abstract available

Keywords: Editorials; biomarkers; ethics and policy.

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References

    1. Kaplan S. Trump considers naming FDA chief who would radically overhaul the agency. December 7, 2016. Available at: https://www.statnews.com/2016/12/07/trump-fda-oneill/. Accessed February 21, 2017.
    1. Bikdeli B, Punnanithinont N, Akram Y, Lee I, Desai N, Ross J, Krumholz H. Two decades of cardiovascular trials with primary surrogate endpoints: 1990–2011. J Am Heart Assoc. 2017;6:e005285 DOI: . - DOI - PMC - PubMed
    1. Coller BS, Califf RM. Traversing the valley of death: a guide to assessing prospects for translational success. Sci Transl Med. 2009;1:10cm9. - PMC - PubMed
    1. Smietana K, Siatkowski M, Moller M. Trends in clinical success rates. Nat Rev Drug Discov. 2016;15:379–380. - PubMed
    1. FDA‐NIH Working Group . BEST (Biomarkers, EndpointS, and other Tools) resource. Available at: https://www.ncbi.nlm.nih.gov/books/NBK326791/. Accessed February 20, 2017.

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