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. 2015 Dec 2;18(7Suppl 6):20770.
doi: 10.7448/IAS.18.7.20770. eCollection 2015.

Getting to 90-90-90 in paediatric HIV: What is needed?

Mary-Ann Davies, Jorge Pinto, Marlène Bras

Getting to 90-90-90 in paediatric HIV: What is needed?

Mary-Ann Davies et al. J Int AIDS Soc. .
No abstract available

Keywords: 90-90-90 target; AIDS; ART; HIV; HIV comorbidities; HIV drug resistance; HIV prevention; HIV/AIDS; PITC; SMS; adherence; adolescents; antiretroviral adherence; antiretroviral therapy; antiretroviral treatment; antiretrovirals; child survival; children; development; diagnosis; double dividend; epidemiology; formulations; guidelines; infant; integration; low birth weight; low- and middle-income countries; management; maternal-child health; non-nucleoside reverse transcriptase inhibitor; optimization; paediatric HIV; perinatal HIV infection; point of care; premature; prevention of mother-to-child HIV transmission; protease inhibitor; psychological complications; small for gestation; social protection; transition; treatment; tuberculosis.

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Figures

Figure 1
Figure 1
Strategies to achieve 90–90–90 for children and adolescents.
Figure 1
Figure 1
Estimated annual proportion of infected infants tested by two months of age in 2014 and estimated proportion of identified infected infants treated. Gap A represents the difference between infants currently receiving early infant diagnosis and the testing target of 90% of all positives, while Gap B represents the difference between infants treated and the treatment target of 90% of identified positives. Data sources: *Estimated number of new child infections in 2014 and estimated coverage of early infant diagnosis testing in 2014 taken from Global AIDS Response Progress Report, WHO, Geneva 2015 [7]. #Proportion of infected infants receiving treatment from Chatterjee et al. BMC Public Health, 2011 [8].
Figure 1
Figure 1
Summary estimates of virological suppression in children <3 years in LMIC, 6 to 24 months after first-line treatment initiation for NNRTI- and PI-treated children. Random effects meta-analysis was conducted using a Freeman–Tukey arcsine square root transformation to stabilize proportions. No virological suppression rates were available for PI-treated children after 18 and 24 months. NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor.
Figure 1
Figure 1
Medium- and long-term priorities for drug sequencing in children [13].
Figure 1
Figure 1
Kaplan–Meier survival by tuberculosis status among children on antiretroviral therapy.
Figure 2
Figure 2
Nelson–Aalen loss to follow-up by tuberculosis status.
Figure 1
Figure 1
Impacts of cash and care provision on HIV-risk behaviour among adolescents in South Africa (marginal effects models, controlling for covariates) [34].
See this image and copyright information in PMC

References

    1. UNAIDS. 90-90-90 An ambitious treatment target to help end the AIDS epidemic. Geneva, Switzerland: UNAIDS; 2014. JC2684.
    1. Abrams E, Strasser S. 90-90-90 – Charting a steady course to end the pediatric HIV epidemic. J Int AIDS Soc. 2015;18(Suppl 6):20296. doi: http://dx.doi.org/10.7448/IAS.18.7.20296. - DOI - PMC - PubMed
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