ILC-poiesis: Making Tissue ILCs from Blood
- PMID: 28329700
- DOI: 10.1016/j.immuni.2017.03.002
ILC-poiesis: Making Tissue ILCs from Blood
Abstract
The development of human innate lymphoid cells (ILCs) remains poorly characterized. In a recent issue of Cell, Lim et al. show that human peripheral-blood CD117+ ILCs harbor ILC precursors (ILCPs) derived from hematopoietic stem cells. Peripheral-blood ILCPs can generate all ILC subsets in vivo and in vitro.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.Cell. 2017 Mar 9;168(6):1086-1100.e10. doi: 10.1016/j.cell.2017.02.021. Cell. 2017. PMID: 28283063
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