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Review
. 2016 Jun;6(1):81.
doi: 10.1007/s13205-016-0368-z. Epub 2016 Feb 23.

Insight into thermophiles and their wide-spectrum applications

Ridhi Mehta  1 , Paavan Singhal  1 , Hardeep Singh  1 , Dhanashree Damle  2 , Anil K Sharma  3
Affiliations
Review

Insight into thermophiles and their wide-spectrum applications

Ridhi Mehta et al. 3 Biotech. 2016 Jun.

Abstract

The deconstruction of biomass is a pivotal process for the manufacture of target products using microbial cells and their enzymes. But the enzymes that possess a significant role in the breakdown of biomass remain relatively unexplored. Thermophilic microorganisms are of special interest as a source of novel thermostable enzymes. Many thermophilic microorganisms possess properties suitable for biotechnological and commercial use. There is, indeed, a considerable demand for a new generation of stable enzymes that are able to withstand severe conditions in industrial processes by replacing or supplementing traditional chemical processes. This manuscript reviews the pertinent role of thermophilic microorganisms as a source for production of thermostable enzymes, factors afftecting them, recent patents on thermophiles and moreso their wide spectrum applications for commercial and biotechnological use.

Keywords: Heat tolerance and biomass; Thermophilic microorganisms; Thermostable enzymes.

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Conflict of interest statement

There exists no conflict of interest regarding publication of this manuscript.

Figures

Fig. 1
Fig. 1
Various applications of thermophilic microorganisms
See this image and copyright information in PMC

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References

    1. Alqueres SMC, Almeida RV, Clementino MM, Vieira RP, Almeida WI, Cardoso AM, Martins OB. Exploring the biotechnological applications in the archeal domain. Brazil J Microbiol. 2007;38:398–405. doi: 10.1590/S1517-83822007000300002. - DOI
    1. Antranikian G, Vorgias CE, Bertoldo C. Extreme environments as a resource for microorganisms and novel biocatalysts. Adv Biochem Eng Biotechnol. 2005;96:219–262. - PubMed
    1. April TM, Foght JM, Currah RS. Hydrocarbon-degrading fungi isolated from flare pit soils in northern and western Canada. Can J Microbiol. 2000;46:38–49. doi: 10.1139/cjm-46-1-38. - DOI - PubMed
    1. Arima K, Liu WH, Beppu T. Studies on the lipase of thermophilic fungus Humicola lanuginosa. Agric Biol Chem. 1972;36:893–895. doi: 10.1080/00021369.1972.10860340. - DOI
    1. Bajaj BK, Sharma M, Rao RS. Agricultural residues for production of cellulase from Sporotrichum thermophile LAR5 and its application for saccharification of rice straw. J Mater Environ Sci. 2014;5(5):1454–1460.

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