Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Mar 22:2017:bcr2016219048.
doi: 10.1136/bcr-2016-219048.

Pulmonary Kaposi sarcoma presenting as complete lung consolidation

Ahmad Alwassia  1 , Ziyad Alshathri  1 , Rahul Khosla  2 , Samuel V Spagnolo  2
Affiliations
Case Reports

Pulmonary Kaposi sarcoma presenting as complete lung consolidation

Ahmad Alwassia et al. BMJ Case Rep. .

Abstract

The patient in our case presented with progressive dyspnoea and cough. Chest radiograph reveals complete opacification of the hemithorax. Complete lung consolidation was not seen on chest CT. The patient in this case had extensive pulmonary and endobronchial Kaposi sarcoma (KS) that led to complete consolidation of the right lung that was diagnosed via bronchoscopy. After diagnosis, he was restarted on antiretroviral therapy and single-agent chemotherapy for treatment of pulmonary KS.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Chest radiograph with complete opacification of the right hemithorax, and multiple nodular opacities in the left lung field.
Figure 2
Figure 2
CT chest showing complete consolidation of the right lung with airbronchograms, right pleural effusion and multiple nodular opacities in the left lung centred around the bronchovascular bundles.
Figure 3
Figure 3
Bronchoscopic view showing narrowed right middle and lower lobe bronchi with diffuse red vascular lesions, biopsy forceps are in the right side of the image.
Figure 4
Figure 4
Histology of the endobronchial biopsy sample. (A) Spindle cells noted with ectatic blood vessels. (B) Spindle cells stain positive for CD31, CD34 in (C) and HHV-8 in (D).
Figure 5
Figure 5
CT chest 4 weeks after initiation of chemotherapy.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Lodi S, Guiguet M, Costagliola D et al. . Kaposi sarcoma incidence and survival among HIV-infected homosexual men after HIV seroconversion. J Natl Cancer Inst 2010;102:784 10.1093/jnci/djq134 - DOI - PMC - PubMed
    1. Joshi M, Markelova N, Palacio D et al. . A patient with HIV, dyspnea, and multiple pulmonary nodules: pulmonary Kaposi sarcoma. Chest 2006;130:1924 10.1378/chest.130.6.1924 - DOI - PubMed
    1. Haramati LB, Wong J. Intrathoracic Kaposi's sarcoma in women with AIDS. Chest 2000;117:410–14.. 10.1378/chest.117.2.410 - DOI - PubMed
    1. Huang L, Schnapp LM, Gruden JF et al. . Presentation of AIDS-related pulmonary Kaposi's sarcoma diagnosed by bronchoscopy. Am J Respir Crit Care Med 1996;153:1385 10.1164/ajrccm.153.4.8616570 - DOI - PubMed
    1. Pinzone MR, Berretta M, Cacopardo B et al. . Epstein-Barr virus- and Kaposi sarcoma-associated herpes virus-related malignancies in the setting of human immunodeficiency virus infection. Semin Oncol 2015;42:258 10.1053/j.seminoncol.2014.12.026 - DOI - PubMed

Publication types

MeSH terms