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. 2015 Apr 1;11(2):88-91.
doi: 10.5152/tjbh.2015.2492. eCollection 2015 Apr.

Mastalgia-Cancer Relationship: A Prospective Study

Affiliations

Mastalgia-Cancer Relationship: A Prospective Study

Ali Cihat Yıldırım et al. J Breast Health. .

Abstract

Objective: Mastalgia is an important symptom affecting approximately 70% of women and it disrupts the quality of life especially due to the worry of having cancer. In our study, the type and severity of mastalgia symptom of patients who presented to the outpatient clinic with mastalgia complaint were assessed along with their physical examination findings and radiology results. The purpose of the study is to demonstrate the relationship between mastalgia and malignity when assessed in combination with the risk factors of patients.

Materials and methods: The age, family history, menopausal status, age at the first childbirth, menarche, presence/absence of hormone replacement therapy, type of mastalgia, comorbidities and examination findings of 104 patients, who presented to the General Surgery outpatient clinic with mastalgia symptom, were recorded and assessed in the light of radiological study results.

Results: With respect to the mastalgia types of the patients, 38.5% had cyclic pain, 57.7% non-cyclic pain and 3.8% other types of pain. Mild mastalgia was present in 46.2% of the patients, moderate mastalgia in 24% and severe mastalgia in 29.8% of them. According to the BIRADS category, 48.1% of the patients were identified to have BIRADS 1 mass lesions, 39.4% BIRADS 2, 9.6% BIRADS 3 and 2.9% BIRADS 5 mass lesions. The patients who were identified to have BIRADS 5 mass lesions described non-cyclic and severe pain in the post-menopausal period. They had palpable masses along with the pain symptom.

Conclusion: Our study suggests that mastalgia symptom does not per se result in suspicion of malignancy, but physical examination and radiological imaging should also be used as needed for confirmation. Studies with a larger patient population are needed to shed light on the mastalgia epidemiology and its relationship with cancer.

Keywords: Mastodynia; breast cancer; mammography; ultrasonography.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
Percentage rates of mastalgia types
Figure 2
Figure 2
Percentage rates of mastalgia severity
Figure 3
Figure 3
Patient percentages according to BIRADS classification

References

    1. Parlati E, Travaglini A, Liberale I, Menini E, Dell’Acqua S. Hormonal profile in benign breast disease. Endocrine status of cyclical mastalgia patients. J Endocrinol Invest. 1988;11:679–683. http://dx.doi.org/10.1007/BF03350214. - DOI - PubMed
    1. Gregl A. Conservative therapy of mastopathy. Med Welt. 1979;30:264–268. - PubMed
    1. BeLieu RM. Mastodynia. Obstet Gynecol Clin North Am. 1994;21:461–477. - PubMed
    1. Duijm LE, Guit GL, Hendriks JH, Zaat JO, Mali WP. Value of breast imaging in women with painful breasts: observational follow up study. BMJ. 1998;317:1492–1495. http://dx.doi.org/10.1136/bmj.317.7171.1492. - DOI - PMC - PubMed
    1. Mansel RE, Webster David JT, Hughes Helen Sweetland. Mansel & Webster’s Benign Disorders and Diseases of the Breast. 3th edition. Saunder Elsevier; 2009. Breast Pain and nodularity; pp. 107–138.

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