Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Apr;20(2):81-83.
doi: 10.1016/j.cjtee.2016.12.002. Epub 2017 Feb 24.

Treatment of cerebrospinal fluid leak after spine surgery

Zhao Fang  1 , Rong Tian  2 , Yu-Tao Jia  1 , Tian-Tong Xu  1 , Yang Liu  1
Affiliations
Review

Treatment of cerebrospinal fluid leak after spine surgery

Zhao Fang et al. Chin J Traumatol. 2017 Apr.

Abstract

Owing to the complexity of spinal surgery, there is a great prevalence of dural tear causing cerebrospinal fluid (CSF) leakage. Many studies focused on suture repair for dural tear to stop CSF leak. Now some new treatment strategies have shown a promising effect that is listed as follows: 1) creating watertight dural closure to stop CSF leak with the help of dural substitute material; and 2) retarding CSF leak by changing pressure difference, including reducing the subarachnoid fluid pressure, increasing the epidural space pressure and both. In fact several methods mentioned above are usually combined to treat CSF leak. However, no update review summarized the relevant studies implemented in recent years. In this review, the authors would compare the effects of different dural closure techniques, and introduce the latest treatment methods and mechanisms.

Keywords: Cerebralspinal fluid leak; Spine; Therapeutics.

PubMed Disclaimer

References

    1. Lenart M.J., Carness J.M. Cerebrospinal fluid-cutaneous fistula after continuous spinal catheter in an obstetric patient. AA Case Rep. 2016;7:103–107. - PubMed
    1. Kothe R., Quante M., Engler N. The effect of incidental dural lesions on outcome after decompression surgery for lumbar spinal stenosis: results of a multi-center study with 800 patients. Eur Spine J. 2016 Apr 28 [Epub ahead of print]. https://www.ncbi.nlm.nih.gov/pubmed/?term=Kothe+R%2C+Quante+M%2C+Engler+N. - PubMed
    1. Kaloostian P.E., Kim J.E., Bydon A. Intracranial hemorrhage after spine surgery. J Neurosurg Spine. 2013;19:370–380. - PubMed
    1. Thomas A., Shetty A.P., Rajasekaran S. Abducens nerve palsy associated with pseudomeningocele after lumbar disc surgery: a case report. Spine (Phila Pa 1976) 2012;37:E511–E513. - PubMed
    1. Menon S.K., Onyia C.U. A short review on a complication of lumbar spine surgery: CSF leak. Clin Neurol Neurosurg. 2015;139:248–251. - PubMed