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. 2017 Oct;40(5):784-793.
doi: 10.1007/s10865-017-9843-1. Epub 2017 Mar 23.

Medical mistrust as a key mediator in the association between perceived discrimination and adherence to antiretroviral therapy among HIV-positive Latino men

Frank H Galvan  1 , Laura M Bogart  2 , David J Klein  2 , Glenn J Wagner  2 , Ying-Tung Chen  3
Affiliations

Medical mistrust as a key mediator in the association between perceived discrimination and adherence to antiretroviral therapy among HIV-positive Latino men

Frank H Galvan et al. J Behav Med. 2017 Oct.

Abstract

Discrimination has been found to have deleterious effects on physical health. The goal of the present study was to examine the association between perceived discrimination and adherence to antiretroviral therapy (ART) among HIV-positive Latino men and the extent to which medical mistrust serves as a mediator of that association. A series of linear and logistic regression models was used to test for mediation for three types of perceived discrimination (related to being Latino, being perceived as gay and being HIV-positive). Medical mistrust was found to be significantly associated with perceived discrimination based on Latino ethnicity and HIV serostatus. Medical mistrust was found to mediate the associations between two types of perceived discrimination (related to being Latino and being HIV-positive) and ART adherence. Given these findings, interventions should be developed that increase the skills of HIV-positive Latino men to address both perceived discrimination and medical mistrust.

Keywords: Antiretroviral therapy; Discrimination; HIV/AIDS; Latino/Hispanic; Medication adherence; Men who have sex with men.

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