Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Apr 7;19(7):1562-1565.
doi: 10.1021/acs.orglett.7b00363. Epub 2017 Mar 24.

Pd-Catalyzed Direct ortho-C-H Arylation of Aromatic Ketones Enabled by a Transient Directing Group

Jiancong Xu  1 , Yang Liu  1 , Ying Wang  1 , Yajuan Li  1 , Xiaohua Xu  1 , Zhong Jin  1
Affiliations

Pd-Catalyzed Direct ortho-C-H Arylation of Aromatic Ketones Enabled by a Transient Directing Group

Jiancong Xu et al. Org Lett. .

Abstract

The Pd-catalyzed direct C(sp2)-H arylation of aromatic ketones using a transient directing group is described. The ketimine/carboxylate bidentate directing group in situ generated from aromatic ketone and glycine enabled a palladium-catalyzed ortho-C-H arylation, which shows extensive substrate compatibility.

PubMed Disclaimer

Publication types

LinkOut - more resources