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Case Reports
. 2016 Aug 30;3(4):e005047.
doi: 10.1099/jmmcr.0.005047. eCollection 2016 Aug.

Non-traumatic keratitis due to Colletotrichum truncatum

Reina Llamos  1 , Abdullah M S Al-Hatmi  2 , Gerardo Martínez  3 , Ferry Hagen  4 , Rosario Velar  3 , Alexeide de la Caridad Castillo Pérez  5 , Jacques F Meis  6 , María T Illnait-Zaragozí  3
Affiliations
Case Reports

Non-traumatic keratitis due to Colletotrichum truncatum

Reina Llamos et al. JMM Case Rep. .

Abstract

Introduction: The fungal genus Colletotrichum is an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation.

Case presentation: We report two cases of keratitis due Colletotrichum truncatum in middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0.25 mg l-1. Both patients failed topical antifungal treatment and needed penetrating keratoplasty with a favourable outcome.

Conclusion: C. truncatum caused keratomycosis which did not respond to topical antifungal agents. To the best of our knowledge these are the first reported cases of keratitis due to this fungus in Cuba and Latin-America and highlights the expanding spectrum of fungal agents causing eye infections.

Keywords: Colletotrichum; keratomycosis; mycotic keratitis.

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Figures

Fig. 1.
Fig. 1.
Morphological description of Colletotrichum truncatum. (a) Growth of the isolate on MEA, slightly olivaceous-grey to iron-grey; (b) brown to pale reverse pigmentations; (c) setae; (d) conidiogenous cells; (e) septate hyphae and conidiophores; (f) conidia. Pictures were taken using a Nikon digital-sight DS-5 M camera attached to the microscope. Bars, 10 µm
See this image and copyright information in PMC

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