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Review
. 2017 Mar 15:11:547-559.
doi: 10.2147/PPA.S127277. eCollection 2017.

Relationship between depression and medication adherence in cardiovascular disease: the perfect challenge for the integrated care team

Affiliations
Review

Relationship between depression and medication adherence in cardiovascular disease: the perfect challenge for the integrated care team

Carly M Goldstein et al. Patient Prefer Adherence. .

Abstract

Many individuals with cardiovascular disease (CVD) experience depression that is associated with poor health outcomes, which may be because of medication nonadherence. Several factors influence medication adherence and likely influence the relationship between depression and medication adherence in CVD patients. This comprehensive study reviews the existing literature on depression and medication adherence in CVD patients, addresses the methods of and problems with measuring medication adherence, and explains why the integrated care team is uniquely situated to improve the outcomes in depressed CVD patients. This paper also explores how the team can collaboratively target depressive symptoms and medication-taking behavior in routine clinical care. Finally, it suggests the limitations to the integrated care approach, identifies targets for future research, and discusses the implications for CVD patients and their families.

Keywords: cardiovascular disease; collaborative care; compliance; electronic monitoring; integrated care; medication adherence; self-management.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

Figures

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Figure 1
Flow diagram of study selection.

References

    1. American Heart Association Heart disease and stroke statistics – 2013 update: a report from the American Heart Association. Circulation. 2013;127(1):e6–e245. - PMC - PubMed
    1. Frasure-Smith N, Lespérance F. Recent evidence linking coronary heart disease and depression. Can J Psychiatry. 2006;51(12):730–737. - PubMed
    1. Barth J, Schumacher M, Herrmann-Lingen C. Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis. Psychosom Med. 2004;66(6):802–813. - PubMed
    1. Kronish IM, Rieckmann N, Halm EA, et al. Persistent depression affects adherence to secondary prevention behaviors after acute coronary syndromes. J Gen Intern Med. 2006;21(11):1178–1183. - PMC - PubMed
    1. Carney RM, Freedland KE. Depression in patients with coronary heart disease. Am J Med. 2008;121(11B):S20–S27. - PubMed

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