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. 1988 Mar;41(3):373-6.
doi: 10.7164/antibiotics.41.373.

Coumarins as inhibitors of bacterial DNA gyrase

I W Althaus  1 , L Dolak, F Reusser
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Free article

Coumarins as inhibitors of bacterial DNA gyrase

I W Althaus et al. J Antibiot (Tokyo). 1988 Mar.
Free article

Abstract

Chlorobiocic acid and 3-(carbobenzoxyamino)-4,7-dihydroxy-8-methylcoumarin were identified as two new inhibitors of Micrococcus luteus DNA gyrase. Both compounds possess weak antibacterial activity against whole M. luteus cells which indicates that they probably lack efficient transport functions to penetrate the cell envelope.

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