Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Mar 29;17(1):34.
doi: 10.1186/s12886-017-0428-0.

Corneal densitometry changes in a patient with interface fluid syndrome after small incision lenticule extraction

Affiliations
Case Reports

Corneal densitometry changes in a patient with interface fluid syndrome after small incision lenticule extraction

Ke Zheng et al. BMC Ophthalmol. .

Abstract

Background: To report a case of interface fluid syndrome (IFS) following small incision lenticule extraction (SMILE) evaluated with corneal densitometry and optical coherence tomography (OCT).

Case presentation: An 18-year-old man reported sudden vision loss 24 days after SMILE procedure. Intraocular pressure (IOP) was 36.3 mmHg (OD) and 36.7 mmHg (OS) by noncontact tonometry. Moderate corneal edema, interface fluid pocket and haze were observed by OCT and confirmed by corneal densitometry values. Discontinuation of steroids and addition of hypotensive medication were offered immediately. The symptoms were cured after the medication. Changes of corneal densitometry were consistent with the clinical course of IFS.

Conclusion: This case illustrates that it is crucial to be aware that a history of SMILE can also cause IFS. Both OCT and corneal densitometry can serve as auxiliary means to evaluate the clinical course of IFS, and appropriate IOP management is an effective approach.

Keywords: Corneal densitometry; Interface fluid syndrome (IFS); Small incision lenticule extraction (SMILE).

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Representative slit-lamp and OCT photographs at (a) 24 days (b) 25 days (c)27 days postoperatively. a Slitlamp examination revealed interface haze and cornea edema. OCT showed interface fluid accumulation in the cap-bed interface of the both eyes. b Interface haze and cornea edema was relieved under slitlamp examination. OCT showed that interface fluid accumulation in the cap-bed interface of the both eye was also absorbed. c The cornea was clear under slitlamp examination. OCT showed merely mild microdistortions in Bowman’s layer

Similar articles

Cited by

References

    1. Dawson DG, Schmack I, Holley GP, Waring GO, 3rd, Grossniklaus HE, Edelhauser HF. Interface fluid syndrome in human eye bank corneas after LASIK: causes and pathogenesis. Ophthalmology. 2007;114(10):1848–1859. doi: 10.1016/j.ophtha.2007.01.029. - DOI - PubMed
    1. Lyle WA, Jin GJ. Interface fluid associated with diffuse lamellar keratitis and epithelial ingrowth after laser in situ keratomileusis. J Cataract Refract Surg. 1999;25(7):1009–1012. doi: 10.1016/S0886-3350(99)00083-8. - DOI - PubMed
    1. Moya Calleja T, Iribarne Ferrer Y, Sanz Jorge A, Sedo FS. Steroid-induced interface fluid syndrome after LASIK. J Refract Surg. 2009;25(2):235–239. - PubMed
    1. Randleman JB, Lesser GR. Glaucomatous damage from pressure-induced stromal keratopathy after LASIK. J Refract Surg. 2012;28(6):378–379. doi: 10.3928/1081597X-20120517-01. - DOI - PMC - PubMed
    1. Hurmeric V, Wang J, Kymionis GD, Yoo SH. Persistent lamellar interface fluid with clear cornea after Descemet stripping automated endothelial keratoplasty. Cornea. 2011;30(12):1485–1487. doi: 10.1097/ICO.0b013e3182068974. - DOI - PubMed

Publication types

LinkOut - more resources