Recent advances in Japanese encephalitis
- PMID: 28357054
- PMCID: PMC5357037
- DOI: 10.12688/f1000research.9561.1
Recent advances in Japanese encephalitis
Abstract
Japanese encephalitis is a flaviviral disease that is endemic to the South, Southeast Asia, and Asia Oceania regions. Given that about 60% of the world's population (about 7.4 billion) resides in this region (about 4.4 billion), this disease poses a significant threat to global health. Active vaccination campaigns conducted in endemic countries have led to a decrease in the number of reported cases over the years. In this article, we strive to briefly highlight recent advances in understanding the role of microRNAs in disease pathology, focus on providing brief summaries of recent clinical trials in the field of Japanese encephalitis therapeutics, and review the current prophylactic strategies.
Keywords: Japanese encephalitis; Minocycline; flavivirus; microRNA; vaccine.
Conflict of interest statement
Competing interests: The authors declare that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.
References
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- Dutta K, Rangarajan PN, Vrati S, et al. : Japanese encephalitis: pathogenesis, prophylactics and therapeutics. Curr Sci. 2010;98(3):326–334. Reference Source
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