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. 1988 Apr 11;16(7):3005-12.
doi: 10.1093/nar/16.7.3005.

v-jun is a transcriptional activator, but not in all cell-lines

J L Imler  1 , E Ugarte, C Wasylyk, B Wasylyk
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Free PMC article

v-jun is a transcriptional activator, but not in all cell-lines

J L Imler et al. Nucleic Acids Res. .
Free PMC article

Abstract

The recently isolated v-jun oncogene encodes a protein with sequence homology to the transcription factor AP1, as well as a similar DNA binding specificity. We show, by expressing v-jun in F9 embryocarcinoma cells, that v-jun is also a transcriptional activator. However, v-jun expression does not activate transcription in several other cell-lines, suggesting that cell-specific factors are required for v-jun activity.

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References

    1. Nucleic Acids Res. 1981 Dec 11;9(23):6251-64 - PubMed
    1. Cell. 1987 Feb 13;48(3):525-34 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 May;84(9):2848-52 - PubMed
    1. Science. 1987 Dec 4;238(4832):1386-92 - PubMed
    1. Nature. 1987 Jul 16-22;328(6127):254-6 - PubMed

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