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Review
. 2017 Jun;6(2):213-223.
doi: 10.1007/s40121-017-0154-1. Epub 2017 Mar 29.

A Review of Diagnostic Methods for Invasive Fungal Diseases: Challenges and Perspectives

Diego R Falci  1   2 , Claudio M B Stadnik  3   4 , Alessandro C Pasqualotto  5   6
Affiliations
Review

A Review of Diagnostic Methods for Invasive Fungal Diseases: Challenges and Perspectives

Diego R Falci et al. Infect Dis Ther. 2017 Jun.

Abstract

Invasive fungal diseases are associated with a high morbidity and mortality, particularly in the context of immunosuppression. Diagnosis of invasive fungal diseases is usually complicated by factors such as poor clinical suspicion and unspecific clinical findings. Access to modern diagnostic tools is frequently limited in developing countries. Here, we describe five real-life clinical cases from a Brazilian tertiary hospital, in order to illustrate how to best select diagnostic tests in patients with different fungal infections.

Keywords: Antigen detection; Beta-D-glucan; Galactomannan; MALDI-TOF; PCR.

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Figures

Fig. 1
Fig. 1
Magnetic resonance imaging of the thorax, demonstrating bilateral pulmonary nodules (Case 1)
Fig. 2
Fig. 2
Computerized tomography of the thorax, showing multiple pulmonary nodules and patchy infiltrates (Case 2)
See this image and copyright information in PMC

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