Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2017 Mar 30;3(3):CD011618.
doi: 10.1002/14651858.CD011618.pub2.

Return-to-work coordination programmes for improving return to work in workers on sick leave

Affiliations
Meta-Analysis

Return-to-work coordination programmes for improving return to work in workers on sick leave

Nicole Vogel et al. Cochrane Database Syst Rev. .

Abstract

Background: To limit long-term sick leave and associated consequences, insurers, healthcare providers and employers provide programmes to facilitate disabled people's return to work. These programmes include a variety of coordinated and individualised interventions. Despite the increasing popularity of such programmes, their benefits remain uncertain. We conducted a systematic review to determine the long-term effectiveness of return-to-work coordination programmes compared to usual practice in workers at risk for long-term disability.

Objectives: To assess the effects of return-to-work coordination programmes versus usual practice for workers on sick leave or disability.

Search methods: We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 11), MEDLINE, Embase, CINAHL and PsycINFO up to 1 November 2016.

Selection criteria: We included randomised controlled trials (RCTs) that enrolled workers absent from work for at least four weeks and randomly assigned them to return-to-work coordination programmes or usual practice.

Data collection and analysis: Two review authors independently screened titles, abstracts and full-text articles for study eligibility; extracted data; and assessed risk of bias from eligible trials. We contacted authors for additional data where required. We conducted random-effects meta-analyses and used the GRADE approach to rate the quality of the evidence.

Main results: We identified 14 studies from nine countries that enrolled 12,568 workers. Eleven studies focused on musculoskeletal problems, two on mental health and one on both. Most studies (11 of 14) followed workers 12 months or longer. Risk of bias was low in 10 and high in 4 studies, but findings were not sensitive to their exclusion.We found no benefits for return-to-work coordination programmes on return-to-work outcomes.For short-term follow-up of six months, we found no effect on time to return to work (hazard ratio (HR) 1.32, 95% confidence interval (CI) 0.93 to 1.88, low-quality evidence), cumulative sickness absence (mean difference (MD) -16.18 work days per year, 95% CI -32.42 to 0.06, moderate-quality evidence), the proportion of participants at work at end of the follow-up (risk ratio (RR) 1.06, 95% CI 0.86 to 1.30, low-quality evidence) or on the proportion of participants who had ever returned to work, that is, regardless of whether they had remained at work until last follow-up (RR 0.87, 95% CI 0.63 to 1.19, very low-quality evidence).For long-term follow-up of 12 months, we found no effect on time to return to work (HR 1.25, 95% CI 0.95 to 1.66, low-quality evidence), cumulative sickness absence (MD -14.84 work days per year, 95% CI -38.56 to 8.88, low-quality evidence), the proportion of participants at work at end of the follow-up (RR 1.06, 95% CI 0.99 to 1.15, low-quality evidence) or on the proportion of participants who had ever returned to work (RR 1.03, 95% CI 0.97 to 1.09, moderate-quality evidence).For very long-term follow-up of longer than 12 months, we found no effect on time to return to work (HR 0.93, 95% CI 0.74 to 1.17, low-quality evidence), cumulative sickness absence (MD 7.00 work days per year, 95% CI -15.17 to 29.17, moderate-quality evidence), the proportion of participants at work at end of the follow-up (RR 0.94, 95% CI 0.82 to 1.07, low-quality evidence) or on the proportion of participants who had ever returned to work (RR 0.95, 95% CI 0.88 to 1.02, low-quality evidence).We found only small benefits for return-to-work coordination programmes on patient-reported outcomes. All differences were below the minimal clinically important difference (MID).

Authors' conclusions: Offering return-to-work coordination programmes for workers on sick leave for at least four weeks results in no benefits when compared to usual practice. We found no significant differences for the outcomes time to return to work, cumulative sickness absence, the proportion of participants at work at end of the follow-up or the proportion of participants who had ever returned to work at short-term, long-term or very long-term follow-up. For patient-reported outcomes, we found only marginal effects below the MID. The quality of the evidence ranged from very low to moderate across all outcomes.

PubMed Disclaimer

Conflict of interest statement

Regina Kunz: EbIM, Evidence‐based Insurance Medicine at the University Hospital in Basel, is funded in part by donations from public insurance companies and a consortium of private insurance companies without restrictions on how the donations are used.

Nicole Vogel: None known.

Stefan Schandelmaier: None known.

Thomas Zumbrunn: employer received payment for the statistical analyses he conducted for the publication on which this review is based.

Shanil Ebrahim: None known.

Wout de Boer: None known.

Jason Busse: acts as a consultant to Prisma Health Canada, a private incorporated company funded by employers and insurers that consults on and manages long‐term disability claims.

Figures

1
1
PRISMA Study flow diagram
2
2
Risk of bias graph: review author's judgements about each risk of bias item presented as percentages across all included studies.
3
3
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
4
4
Forest plot of comparison: time to return to work. RTWCP = return‐to‐work coordination programmes
5
5
Forest plot of comparison: cumulative sickness absence in work days. RTWCP = return‐to‐work coordination programmes
6
6
Forest plot of comparison: proportion at work at end of the follow‐up. RTWCP = return‐to‐work coordination programmes
7
7
Forest plot of comparison: proportion who had ever returned to work. RTWCP = return‐to‐work coordination programmes

Update of

  • doi: 10.1002/14651858.CD011618

References

References to studies included in this review

Bültmann 2009 {published data only}
    1. Bültmann U, Sherson D, Olsen J, Hansen CL, Lund T, Kilsgaard J. Coordinated and tailored work rehabilitation: a randomized controlled trial with economic evaluation undertaken with workers on sick leave due to musculoskeletal disorders. Journal of Occupational Rehabilitation 2009;19(1):81‐93. - PubMed
Davey 1994 {published data only}
    1. Davey CA. The Implementation and Evaluation of a Rehabilitation Co‐ordinator Service for Personal Injury Claimants. Edinburgh: University of Edinburgh, 1994. - PubMed
Donceel 1999 {published data only}
    1. Donceel P, Du Bois M, Lahaye D. Return to work after surgery for lumbar disc herniation. A rehabilitation‐oriented approach in insurance medicine. Spine 1999;24(9):872‐6. - PubMed
Feuerstein 2003 {published and unpublished data}
    1. Feuerstein M, Huang GD, Ortiz JM, Shaw WS, Miller VI, Wood PM. Integrated case management for work‐related upper‐extremity disorders: impact of patient satisfaction on health and work status. Journal of Occupational and Environmental Medicine 2003;45(8):803‐12. - PubMed
Jensen 2012 {published data only}
    1. Jensen C, Jensen OK, Nielsen CV. Sustainability of return to work in sick‐listed employees with low‐back pain. Two‐year follow‐up in a randomized clinical trial comparing multidisciplinary and brief intervention. BMC Musculoskeletal Disorders 2012;13:156. [DOI: 10.1186/1471-2474-13-156] - DOI - PMC - PubMed
Lambeek 2010 {published data only}
    1. Lambeek LC, Mechelen W, Knol DL, Loisel P, Anema JR. Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life. BMJ 2010;340:c1035. [DOI: 10.1136/bmj.c1035] - DOI - PMC - PubMed
Lindh 1997 {published data only}
    1. Lindh M, Lurie M, Sann H. A randomized prospective study of vocational outcome in rehabilitation of patients with non‐specific musculoskeletal pain: A multidisciplinary approach to patients identified after 90 days of sick‐leave. Scandinavian Journal of Rehabilitation Medicine 1997;29(2):103‐12. - PubMed
Myhre 2014 {published and unpublished data}
    1. Myhre K, Marchand GH, Leivseth G, Keller A, Bautz‐Holter E, Sandvik L, et al. The effect of work‐focused rehabilitation among patients with neck and back pain: a randomized controlled trial. Spine 2014;39(24):1999‐2006. - PubMed
Purdon 2006 {published data only}
    1. Purdon S, Stratford N, Taylor R, Natarajan L, Bell S, Wittenburg D. Impacts of the job retention and rehabilitation pilot. Leeds: Department for Work and Pensions. 2006. Research Report No 342.
Rossignol 2000 {published data only}
    1. Rossignol M, Abenhaim L, Seguin P, Neveu A, Collet JP, Ducruet T, et al. Coordination of primary health care for back pain. A randomized controlled trial. Spine 2000;25(2):251‐8; discussion 258‐9. - PubMed
Scholz 2015 {published data only}
    1. Scholz SM, Andermatt P, Tobler BL, Spinnler D. Work incapacity and treatment costs after severe accidents: standard vs. intensive case management in a 6‐year randomized controlled trial. Journal of Occupational Rehabilitation 2016;26(3):319‐31. - PMC - PubMed
Stapelfeldt 2011 {published and unpublished data}
    1. Stapelfeldt CM, Christiansen DH, Jensen OK, Nielsen CV, Petersen KD, Jensen C. Subgroup analyses on return to work in sick‐listed employees with low back pain in a randomised trial comparing brief and multidisciplinary intervention. BMC Musculoskeletal Disorders 2011;12:112. [DOI: 10.1186/1471-2474-12-112] - DOI - PMC - PubMed
Van der Feltz‐Cornelis 2010 {published data only}
    1. Feltz‐Cornelis CM, Hoedeman R, Jong FJ, Meeuwissen JA, Drewes HW, Laan NC, et al. Faster return to work after psychiatric consultation for sicklisted employees with common mental disorders compared to care as usual. A randomized clinical trial. Journal of Neuropsychiatric Disease and Treatment 2010;6:375‐85. - PMC - PubMed
Volker 2015 {published and unpublished data}
    1. Volker D, Zijlstra‐Vlasveld MC, Anema JR, Beekman AT, Brouwers EP, Emons WH, et al. Effectiveness of a blended web‐based intervention on return to work for sick‐listed employees with common mental disorders: results of a cluster randomized controlled trial. Journal of Medical Internet Research 2015;17(5):e116. - PMC - PubMed

References to studies excluded from this review

Abásolo 2005 {published data only}
    1. Abásolo L, Blanco M, Bachiller J, Candelas G, Collado P, Lajas C, et al. A health system program to reduce work disability related to musculoskeletal disorders. Annals of Internal Medicine 2005;143(6):404‐14. - PubMed
Abásolo 2007 {published data only}
    1. Abásolo L, Carmona L, Hernandez‐Garcia C, Lajas C, Loza E, Blanco M, et al. Musculoskeletal work disability for clinicians: time course and effectiveness of a specialized intervention program by diagnosis. Arthritis & Rheumatology 2007;57(2):335‐42. - PubMed
Alaranta 1986 {published data only}
    1. Alaranta H, Hurme M, Einola S, Kallio V, Knuts LR, Törmä T. Rehabilitation after surgery for lumbar disc herniation: results of a randomized clinical trial. International Journal of Rehabilitation Research 1986;9(3):247‐57. - PubMed
Alaranta 1994 {published data only}
    1. Alaranta H, Rytokoski U, Rissanen A, Talo S, Ronnemaa T, Puukka P, et al. Intensive physical and psychosocial training program for patients with chronic low back pain. A controlled clinical trial. Spine 1994;16(12):1339‐49. - PubMed
Andersen 2015 {published data only}
    1. Andersen LN, Juul‐Kristensen B, Roessler KK, Herborg LG, Sorensen TL, Sogaard K. Efficacy of 'Tailored Physical Activity' on reducing sickness absence among health care workers: a 3‐months randomised controlled trial. Manual therapy 2015; Vol. 20, issue 5:666‐71. - PubMed
Anema 2007 {published data only}
    1. Anema JR, Steenstra IA, Bongers PM, Vet HC, Knol DL, Loisel P, et al. Multidisciplinary rehabilitation for subacute low back pain: graded activity or workplace intervention or both? A randomized controlled trial. Spine 2007;32(3):291‐8. - PubMed
Arnetz 2003 {published data only}
    1. Arnetz BB, Sjogren B, Rydehn B, Meisel R. Early workplace intervention for employees with musculoskeletal‐related absenteeism: a prospective controlled intervention study. Journal of Occupational and Environmental Medicine 2003;45(5):499‐506. - PubMed
Bakker 2007 {published data only}
    1. Bakker IM, Terluin B, van‐Marwijk HWJ, Windt DAWM, Rijmen F, van MW, et al. A cluster‐randomised trial evaluating an intervention for patients with stress‐related mental disorders and sick leave in primary care. PLOS Clinical Trials 2007;2(6):e26. - PMC - PubMed
Berg 2011 {published data only}
    1. Berg SK, Svendsen JH, Zwisler AD, Pedersen BD, Preisler P, Siersbaek‐Hansen L, et al. COPE‐ICD: a randomised clinical trial studying the effects and meaning of a comprehensive rehabilitation programme for ICD recipients ‐design, intervention and population. BMC Cardiovascular Disorders 2011;11:33. [DOI: 10.1186/1471-2261-11-33] - DOI - PMC - PubMed
Bergström 2012 {published data only}
    1. Bergström C, Jensen I, Hagberg J, Busch H, Bergstrom G. Effectiveness of different interventions using a psychosocial subgroup assignment in chronic neck and back pain patients: a 10‐year follow‐up. Disability and Rehabilitation 2012;34(2):110‐8. - PubMed
Bethge 2010 {published data only}
    1. Bethge M, Herbold D, Trowitzsch L, Jacobi C. Return to work following work‐related orthopaedic rehabilitation: a cluster randomized trial. Rehabilitation 2010;49(1):2‐12. - PubMed
Bethge 2011 {published data only}
    1. Bethge M, Herbold D, Trowitzsch L, Jacobi C. Work status and health‐related quality of life following multimodal work hardening: a cluster randomised trial. Journal of Back and Musculoskeletal Rehabilitation 2011;24(3):161‐72. - PubMed
Beutel 2005 {published data only}
    1. Beutel ME, Zwerenz R, Bleichner F, Vorndran A, Gustson D, Knickenberg RJ. Vocational training integrated into inpatient psychosomatic rehabilitation‐‐short and long‐term results from a controlled study. Disability and Rehabilitation 2005;27(15):891‐900. - PubMed
Bishop 2014 {published data only}
    1. Bishop A, Wynne‐Jones G, Lawton SA, Windt D, Main C, Sowden G, et al. Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669). BMC Musculoskeletal Disorders 2014;15:232. [DOI: 10.1186/1471-2474-15-232] - DOI - PMC - PubMed
Bjorneklett 2013 {published data only}
    1. Bjorneklett HG, Rosenblad A, Lindemalm C, Ojutkangas ML, Letocha H, Strang P, et al. A randomized controlled trial of support group intervention after breast cancer treatment: results on sick leave, health care utilization and health economy. Acta Oncologica 2013;52(1):38‐47. - PubMed
Blonk 2006 {published data only}
    1. Blonk RWB, Brenninkmeijer V, Lagerveld SE, Houtman ILD. Return to work: a comparison of two cognitive behavioural interventions in cases of work‐related psychological complaints among the self‐employed. Work and Stress 2006;20(2):129‐44.
Bohman 2011 {published data only}
    1. Bohman TM, Wallisch L, Christensen KB, Stoner B, Pittman A, Reed B, et al. Working Well ‐ the Texas demonstration to maintain indenpendence and employment: 18‐month outcomes. Journal of Vocational Rehabilitation 2011;34(2):97‐106.
Bonde 2005 {published data only}
    1. Bonde JP, Rasmussen MS, Hjøllund H, Svendsen SW, Kolstad HA, Jensen LD, et al. Occupational disorders and return to work: a randomized controlled study. Journal of Rehabilitation Medicine 2005;37(4):230‐5. - PubMed
Bouwsma 2014 {published data only}
    1. Bouwsma EV, Anema JR, Vonk Noordegraaf A, Knol DL, Bosmans JE, Schraffordt Koops SE, et al. The cost effectiveness of a tailored, web‐based care program to enhance postoperative recovery in gynecologic patients in comparison with usual care: protocol of a stepped wedge cluster randomized controlled trial. JMIR Research Protocols 2014;3(2):e30. - PMC - PubMed
Braathen 2007 {published data only}
    1. Braathen TN, Veiersted KB, Heggenes J. Improved work ability and return to work following vocational multidisciplinary rehabilitation of subjects on long‐term sick leave. Journal of Rehabilitation Medicine 2007;39(6):493‐9. - PubMed
Brendbekken 2016 {published data only}
    1. Brendbekken R, Eriksen HR, Grasdal A, Harris A, Hagen EM, Tangen T. Return to work in patients with chronic musculoskeletal pain: multidisciplinary intervention versus brief intervention: a randomized clinical trial. Journal of Occupational Rehabilitation 2016; Vol. 27, issue 1:82‐91. [DOI: 10.1007/s10926-016-9634-5] - DOI - PMC - PubMed
Brouwers 2006 {published data only}
    1. Brouwers EP, Tiemens BG, Terluin B, Verhaak PF. Effectiveness of an intervention to reduce sickness absence in patients with emotional distress or minor mental disorders: a randomized controlled effectiveness trial. General Hospital Psychiatry 2006;28(3):223‐9. - PubMed
Buijs 2009 {published data only}
    1. Buijs PC, Lambeek LC, Koppenrade V, Hooftman WE, Anema JR. Can workers with chronic back pain shift from pain elimination to function restore at work? Qualitative evaluation of an innovative work related multidisciplinary programme. Journal of Back and Musculoskeletal Rehabilitation 2009;22(2):65‐73. - PubMed
Busch 2011 {published data only}
    1. Busch H, Bodin L, Bergstrom G, Jensen IB. Patterns of sickness absence a decade after pain‐related multidisciplinary rehabilitation. Pain 2011;152(8):1727‐33. - PubMed
Byrne 1993 {published data only}
    1. Byrne DM, Drury J, Mackay RC, Robinson S, Faranda C, MacAdam DB. Evaluation of the efficacy of an instructional programme in the self‐management of patients with asthma. Journal of Advanced Nursing 1993;18(4):637‐46. - PubMed
Carlsson 2013 {published data only}
    1. Carlsson L, Englund L, Hallqvist J, Wallman T. Early multidisciplinary assessment was associated with longer periods of sick leave: a randomized controlled trial in a primary health care centre. Scandinavian Journal of Primary Health Care 2013;31(3):141‐6. - PMC - PubMed
Cheadle 1999 {published data only}
    1. Cheadle A, Wickizer TM, Franklin G, Cain K, Joesch J, Kyes K, et al. Evaluation of the Washington State Workers' Compensation Managed Care Pilot Project II: medical and disability costs 639. Medical Care 1999;37(10):982‐93. - PubMed
Cheng 2007 {published data only}
    1. Cheng AS, Hung LK. Randomized controlled trial of workplace‐based rehabilitation for work‐related rotator cuff disorder. Journal of Occupational Rehabilitation 2007;17(3):487‐503. - PubMed
De Boer 2004 {published data only}
    1. Boer AG, Beek JC, Durinck J, Verbeek JH, Dijk FJ. An occupational health intervention programme for workers at risk for early retirement; a randomised controlled trial. Occupational and Environmental Medicine 2004;61(11):924‐9. - PMC - PubMed
De Boer 2007 {published data only}
    1. Boer AG, Burdorf A, Duivenbooden C, Frings‐Dresen MH. The effect of individual counselling and education on work ability and disability pension: a prospective intervention study in the construction industry. Occupational and Environmental Medicine 2007;64(12):792‐7. - PMC - PubMed
De Buck 2005 {published data only}
    1. Buck PD, le CS, Hout WB, Peeters AJ, Ronday HK, Westedt ML, et al. Randomized comparison of a multidisciplinary job‐retention vocational rehabilitation program with usual outpatient care in patients with chronic arthritis at risk for job loss. Arthritis & Rheumatology 2005;53(5):682‐90. - PubMed
Della‐Posta 2006 {published data only}
    1. Della‐Posta C, Drummond PD. Cognitive behavioural therapy increases re‐employment of job seeking worker's compensation clients. Journal of Occupational Rehabilitation 2006;16(2):223‐30. - PubMed
Demir 2014 {published data only}
    1. Demir S, Dulgeroglu D, Cakci A. Effects of dynamic lumbar stabilization exercises following lumbar microdiscectomy on pain, mobility and return to work. European Journal of Physical and Rehabilitation Medicine 2014;50(6):627‐40. - PubMed
Demoulin 2010 {published data only}
    1. Demoulin C, Grosdent S, Capron L, Tomasella M, Somville PR, Crielaard JM, et al. Effectiveness of a semi‐intensive multidisciplinary outpatient rehabilitation program in chronic low back pain. Joint Bone Spine 2010;77(1):58‐63. - PubMed
Dibbelt 2006 {published data only}
    1. Dibbelt S, Greitemann B, Büschel C. Long‐term efficiency of orthopedic rehabilitation in chronic back pain‐‐the integrative orthopedic psychosomatic concept (IopKo) [Nachhaltigkeit orthopädischer Rehabilitation bei chronischen Rückenschmerzen ‐ Das Integrierte orthopädisch‐psychosomatische Behandlungskonzept (IopKo)]. Die Rehabilitation 2006;45(6):324‐35. - PubMed
Drews 2007 {published data only}
    1. Drews B, Nielsen CV, Rasmussen MS, Hjort J, Bonde JP. Improving motivation and goal setting for return to work in a population on sick leave: a controlled study. Scandinavian Journal of Public Health 2007;35(1):86‐94. - PubMed
Du Bois 2012 {published data only}
    1. Du Bois M, Donceel P. Guiding low back claimants to work: a randomized controlled trial. Spine 2012;37(17):1425‐31. - PubMed
Ektor‐Andersen 2008 {published data only}
    1. Ektor‐Andersen J, Ingvarsson E, Kullendorff M, Orbaek P. High cost‐benefit of early team‐based biomedical and cognitive‐behaviour intervention for long‐term pain‐related sickness absence. Journal of Rehabilitation Medicine 2008;40(1):1‐8. - PubMed
Ellis 2010 {published data only}
    1. Ellis N, Johnston V, Gargett S, MacKenzie A, Strong J, Battersby M, et al. Does self‐management for return to work increase the effectiveness of vocational rehabilitation for chronic compensated musculoskeletal disorders? Protocol for a randomised controlled trial. BMC Musculoskeletal Disorders 2010;11:115. [DOI: 10.1186/1471-2474-11-115] - DOI - PMC - PubMed
Elvsåshagen 2009 {published data only}
    1. Elvsåshagen H, Tellnes G, Abdelnoor MH. Does early intervention by a specialist in physical medicine and rehabilitation reduce the duration of long term sick leave among persons with musculoskeletal diseases? [Gir tidlig vurdering og behandling hos spesialist i fysikalskmedisin og rehabilitering reduksjon i langtidsfravær hossykmeldte med muskel‐ og skjelettsykdommer?]. Norsk Epidemiologi 2009;19(2):219‐22.
Eshoj 2001 {published data only}
    1. Eshoj P, Tarp U, Nielsen CV. Effect of early vocational intervention in a rheumatological outpatient clinic‐‐a randomized study. International Journal of Rehabilitation Research 2001;24(4):291‐7. - PubMed
Fimland 2014 {published data only}
    1. Fimland MS, Vasseljen O, Gismervik S, Rise MB, Halsteinli V, Jacobsen HB, et al. Occupational rehabilitation programs for musculoskeletal pain and common mental health disorders: study protocol of a randomized controlled trial. BMC Public Health 2014;14:368. [DOI: 10.1186/1471-2458-14-368] - DOI - PMC - PubMed
Frey 2008 {published data only}
    1. Frey WD, Azrin ST, Goldman HH, Kalasunas S, Salkever DS, Miller AL, et al. The mental health treatment study. Psychiatric Rehabilitation Journal 2008;31:306‐12. [DOI: 10.2975/31.4.2008.306.312] - DOI - PubMed
Fritz 2003 {published data only}
    1. Fritz JM, Delitto A, Erhard RE. Comparison of classification‐based physical therapy with therapy based on clinical practice guidelines for patients with acute low back pain: a randomized clinical trial. Spine 2003;28(13):1363‐71. - PubMed
Gatchel 2003 {published data only}
    1. Gatchel RJ, Polatin PB, Noe C, Gardea M, Pulliam C, Thompson J. Treatment‐ and cost‐effectiveness of early intervention for acute low‐back pain patients: a one‐year prospective study. Journal of Occupational Rehabilitation 2003;13(1):1‐9. - PubMed
Greitemann 2006 {published data only}
    1. Greitemann B, Dibbelt S, Büschel C. Multidisciplinary orthopedic rehabilitation program in patients with chronic back pain and need for changing job situation ‐‐ long‐term effects of a multimodal, multidisciplinary program with activation and job development [Integriertes Orthopädisch‐Psychosomatisches Konzept zur medizinischen Rehabilitation von Patienten mit chronischen Schmerzen des Bewegungsapparates ‐ Langfristige Effekte und Nachhaltigkeit eines multimodalen Programmes zur Aktivierung und beruflichen Umorientierung]. Zeitschrift für Orthopädie und ihre Grenzgebiete 2006;144(3):255‐66. - PubMed
Haldorsen 1998 {published data only}
    1. Haldorsen EM, Kronholm K, Skouen JS, Ursin H. Multimodal cognitive behavioral treatment of patients sicklisted for musculoskeletal pain: a randomized controlled study. Scandinavian Journal of Rheumatology 1998;27(1):16‐25. - PubMed
Haldorsen 2002 {published data only}
    1. Haldorsen EM, Grasdal AL, Skouen JS, Risa AE, Kronholm K, Ursin H. Is there a right treatment for a particular patient group? Comparison of ordinary treatment, light multidisciplinary treatment, and extensive multidisciplinary treatment for long‐term sick‐listed employees with musculoskeletal pain. Pain 2002;95(1‐2):49‐63. - PubMed
Hees 2013 {published data only}
    1. Hees HL, Vries G, Koeter MW, Schene AH. Adjuvant occupational therapy improves long‐term depression recovery and return‐to‐work in good health in sick‐listed employees with major depression: results of a randomised controlled trial. Occupational and Environmental Medicine 2013;70(4):252‐60. - PubMed
Henchoz 2010 {published data only}
    1. Henchoz Y, Goumoens P, So AK, Paillex R. Functional multidisciplinary rehabilitation versus outpatient physiotherapy for non specific low back pain: randomized controlled trial. Swiss Medical Weekly 2010;140:w13133. [DOI: 10.4414/smw.2010.13133] - DOI - PubMed
Hlobil 2007 {published data only}
    1. Hlobil H, Uegaki K, Staal JB, de‐Bruyne MC, Smid T, van MW. Substantial sick‐leave costs savings due to a graded activity intervention for workers with non‐specific sub‐acute low back pain. European Spine Journal 2007;16(7):919‐24. - PMC - PubMed
Hoverstad 1994 {published data only}
    1. Hoverstad T, Koefoed G, Gudding IH. Intervention against sick‐leave in an industrial company. Tidsskrift for den Norske lægeforening 1994;114(11):1317‐20. - PubMed
Hubbard 2013 {published data only}
    1. Hubbard G, Gray NM, Ayansina D, Evans JM, Kyle RG. Case management vocational rehabilitation for women with breast cancer after surgery: a feasibility study incorporating a pilot randomised controlled trial. Trials 2013;14:175. [DOI: 10.1186/1745-6215-14-175] - DOI - PMC - PubMed
Huppe 2006 {published data only}
    1. Huppe A, Glaser‐Moller N, Raspe H. Offering multidisciplinary medical rehabilitation to workers with work disability due to musculoskeletal disorders: results of randomized controlled trial [Trägerübergreifendes Projekt zur Früherkennung von Rehabilitationsbedarf bei Versicherten mit muskuloskelettalen Beschwerden durch Auswertung von Arbeitsunfähigkeitsdaten: Ergebnisse einer randomisierten, kontrollierten Evaluationsstudie]. Gesundheitswesen 2006;68(6):347‐56. - PubMed
Indahl 1998 {published data only}
    1. Indahl A, Haldorsen EH, Holm S, Reikeras O, Ursin H. Five‐year follow‐up study of a controlled clinical trial using light mobilization and an informative approach to low back pain. Spine 1998;23(23):2625‐30. - PubMed
Jensen 1995 {published data only}
    1. Jensen I, Nygren A, Gamberale F, Goldie I, Westerholm P, Jonsson E. The role of the psychologist in multidisciplinary treatments for chronic neck and shoulder pain: a controlled cost‐effectiveness study. Scandinavian Journal of Rehabilitation Medicine 1995;27(1):19‐26. - PubMed
Jensen 2013 {published data only}
    1. Jensen AG. A two‐year follow‐up on a program theory of return to work intervention. Work (Reading, MA) 2013;44(2):165‐75. - PubMed
Johansson 1998 {published data only}
    1. Johansson C, Dahl J, Jannert M, Melin L, Andersson G. Effects of a cognitive‐behavioral pain‐management program. Behaviour Research and Therapy 1998;36(10):915‐30. - PubMed
Jousset 2004 {published data only}
    1. Jousset N, Fanello S, Bontoux L, Dubus V, Billabert C, Vielle B, et al. Effects of functional restoration versus 3 hours per week physical therapy: a randomized controlled study. Spine 2004;29(5):487‐93. - PubMed
Karlson 2010 {published data only}
    1. Karlson B, Jonsson P, Palsson B, Abjornsson G, Malmberg B, Larsson B, et al. Return to work after a workplace‐oriented intervention for patients on sick‐leave for burnout‐‐a prospective controlled study. BMC Public Health 2010;10:301. [DOI: 10.1186/1471-2458-10-301] - DOI - PMC - PubMed
Karrholm 2006 {published data only}
    1. Karrholm J, Ekholm K, Jakobsson B, Ekholm J, Bergroth A, Schuldt K. Effects on work resumption of a co‐operation project in vocational rehabilitation. Systematic, multi‐professional, client‐centred and solution‐oriented co‐operation. Disability and Rehabilitation 2006;28(7):457‐67. - PubMed
Karrholm 2008 {published data only}
    1. Karrholm J, Ekholm K, Ekholm J, Bergroth A, Ekholm KS. Systematic co‐operation between employer, occupational health service and social insurance office: a 6‐year follow‐up of vocational rehabilitation for people on sick‐leave, including economic benefits. Journal of Rehabilitation Medicine 2008;40(8):628‐36. - PubMed
Kimbrough 2010 {published data only}
    1. Kimbrough E, Lao L, Berman B, Pelletier KR, Talamonti WJ. An integrative medicine intervention in a Ford Motor Company assembly plant. Journal of Occupational and Environmental Medicine 2010;52(3):256‐7. - PubMed
Kirby 2004 {published data only}
    1. Kirby S, Riley R. Compulsory work‐focused interviews for inactive benefit claimants: an evaluation of the British ONE pilots. Labour Economics 2004;11(4):415‐29.
Kittel 2008 {published data only}
    1. Kittel J, Karoff M. Improvement of worklife participation through vocationally oriented cardiac rehabilitation? Findings of a randomized control group study. Rehabilitation 2008;47(1):14‐22. - PubMed
Klaber Moffett 2004 {published data only}
    1. Klaber Moffett JA, Carr J, Howarth E. High fear‐avoiders of physical activity benefit from an exercise program for patients with back pain. Spine 2004;29(11):1167‐72; discussion 73. - PubMed
Knapp 2015 {published data only}
    1. Knapp S, Briest J, Bethge M. Work‐related rehabilitation aftercare for patients with musculoskeletal disorders: results of a randomized‐controlled multicenter trial. International Journal of Rehabilitation Research 2015; Vol. 38, issue 3:226‐32. - PubMed
Knight 1994 {published data only}
    1. Knight KK, Goetzel RZ, Fielding JE, Eisen M, Jackson GW, Kahr TY, et al. An evaluation of Duke university's LIVE FOR LIFE health promotion program on changes in worker absenteeism. Journal of Occupational and Environmental Medicine 1994;36(5):533‐6. - PubMed
Kornfeld 2000 {published data only}
    1. Kornfeld R, Rupp K. The net effects of the Project NetWork return‐to‐work case management experiment on participant earnings, benefit receipt, and other outcomes. Social Security Bulletin 2000;63(1):12‐33. - PubMed
Kyes 1999 {published data only}
    1. Kyes KB, Wickizer TM, Franklin G, Cain K, Cheadle A, Madden C, et al. Evaluation of the Washington State Workers' Compensation Managed Care Pilot Project I: medical outcomes and patient satisfaction. Medical Care 1999;37(10):972‐81. - PubMed
Lai 2007 {published data only}
    1. Lai HS, Chan CC. Implementing a pilot work injury management program in Hong Kong. Journal of Occupational Rehabilitation 2007;17(4):712‐26. - PubMed
Lamb 2007 {published data only}
    1. Lamb SE, Gates S, Underwood MR, Cooke MW, Ashby D, Szczepura A, et al. Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders. BMC Musculoskeletal Disorders 2007;8:7. - PMC - PubMed
Lerner 2015 {published data only}
    1. Lerner D, Adler DA, Rogers WH, Chang H, Greenhill A, Cymerman E, et al. A randomized clinical trial of a telephone depression intervention to reduce employee presenteeism and absenteeism. Psychiatric Services 2015;66(6):570‐7. - PMC - PubMed
Li 2006 {published data only}
    1. Li EJ, Li‐Tsang CW, Lam CS, Hui KY, Chan CC. The effect of a "training on work readiness" program for workers with musculoskeletal injuries: a randomized control trial (RCT) study. Journal of Occupational Rehabilitation 2006;16(4):529‐41. - PubMed
Linden 2014 {published data only}
    1. Linden M, Muschalla B, Hansmeier T, Sandner G. Reduction of sickness absence by an occupational health care management program focusing on self‐efficacy and self‐management. Work (Reading, MA) 2014;47(4):485‐9. - PubMed
Lindström 1992 {published data only}
    1. Lindström I, Ohlund C, Eek C, Wallin L, Peterson LE, Fordyce WE, et al. The effect of graded activity on patients with subacute low back pain: a randomized prospective clinical study with an operant‐conditioning behavioral approach. Physical Therapy 1992;72(4):279‐90. - PubMed
Lindström 1995 {published data only}
    1. Lindström I, Ohlund C, Nachemson A. Physical performance, pain, pain behavior and subjective disability in patients with subacute low back pain. Scandinavian Journal of Rehabilitation Medicine 1995;27(3):153‐60. - PubMed
Linton 1989 {published data only}
    1. Linton SJ, Bradley LA, Jensen I, Spangfort E, Sundell L. The secondary prevention of low back pain: a controlled study with follow‐up. Pain 1989;36(2):197‐207. - PubMed
Li‐Tsang 2008 {published data only}
    1. Li‐Tsang CW, Li EJ, Lam CS, Hui KY, Chan CC. The effect of a job placement and support program for workers with musculoskeletal injuries: a randomized control trial (RCT) study. Journal of Occupational Rehabilitation 2008;18(3):299‐306. - PubMed
Loisel 2002 {published data only}
    1. Loisel P, Lemaire J, Poitras S, Durand MJ, Champagne F, Stock S, et al. Cost‐benefit and cost‐effectiveness analysis of a disability prevention model for back pain management: a six year follow up study. Occupational and Environmental Medicine 2002;59(12):807‐15. - PMC - PubMed
Magnussen 2007 {published data only}
    1. Magnussen L, Strand LI, Skouen JS, Eriksen HR. Motivating disability pensioners with back pain to return to work‐‐a randomized controlled trial. Journal of Rehabilitation Medicine 2007;39(1):81‐7. - PubMed
Mallon 2008 {published data only}
    1. Mallon TM, Cloeren M, Firestone LM, Burch HC. Contract case managers prove cost effective in federal workers' compensation programs. Military Medicine 2008;173(3):253‐8. - PubMed
Marhold 2001 {published data only}
    1. Marhold C, Linton SJ, Melin L. A cognitive‐behavioral return‐to‐work program: effects on pain patients with a history of long‐term versus short‐term sick leave. Pain 2001;91(1‐2):155‐63. - PubMed
Marnetoft 1999 {published data only}
    1. Marnetoft SU, Selander J, Bergroth A, Ekholm J. Vocational rehabilitation‐‐early versus delayed. The effect of early vocational rehabilitation compared to delayed vocational rehabilitation among employed and unemployed, long‐term sick‐listed people. International Journal of Rehabilitation Research 1999;22(3):161‐170. - PubMed
Marnetoft 2000 {published data only}
    1. Marnetoft SU, Selander J. Multidisciplinary vocational rehabilitation focusing on work training and case management for unemployed sick‐listed people. International journal of rehabilitation research 2000;23(4):271‐9. - PubMed
Martin 2013 {published data only}
    1. Martin MH, Nielsen MB, Madsen IE, Petersen SM, Lange T, Rugulies R. Effectiveness of a coordinated and tailored return‐to‐work intervention for sickness absence beneficiaries with mental health problems. Journal of Occupational Rehabilitation 2013;23(4):621‐30. - PubMed
Matchar 2008 {published data only}
    1. Matchar DB, Harpole L, Samsa GP, Jurgelski A, Lipton RB, Silberstein SD, et al. The headache management trial: a randomized study of coordinated care. Headache 2008;48(9):1294‐310. - PubMed
McCluskey 2006 {published data only}
    1. McCluskey S, Burton AK, Main CJ. The implementation of occupational health guidelines principles for reducing sickness absence due to musculoskeletal disorders. Occupational Medicine 2006;56(4):237‐42. - PubMed
Meijer 2006 {published data only}
    1. Meijer EM, Sluiter JK, Heyma A, Sadiraj K, Frings‐Dresen MH. Cost‐effectiveness of multidisciplinary treatment in sick‐listed patients with upper extremity musculoskeletal disorders: a randomized, controlled trial with one‐year follow‐up. International Archives of Occupational and Environmental Health 2006;79(8):654‐64. - PubMed
Mitchell 1994 {published data only}
    1. Mitchell RI, Carmen GM. The functional restoration approach to the treatment of chronic pain in patients with soft tissue and back injuries. Spine 1994;19(6):633‐42. - PubMed
Mortelmans 2006 {published data only}
    1. Mortelmans AK, Donceel P, Lahaye D, Bulterys S. Does enhanced information exchange between social insurance physicians and occupational physicians improve patient work resumption? A controlled intervention study. Occupational and Environmental Medicine 2006;63(7):495‐502. - PMC - PubMed
Netterstrom 2013 {published data only}
    1. Netterstrom B, Friebel L, Ladegaard Y. Effects of a multidisciplinary stress treatment programme on patient return to work rate and symptom reduction: results from a randomised, wait‐list controlled trial. Psychotherapy and Psychosomatics 2013;82(3):177‐86. - PubMed
Nilsson 1996 {published data only}
    1. Nilsson I, Von BL. An attempt to work rehabilitation after long sick‐leave. Work (Reading, MA) 1996;7(3):183‐9. - PubMed
Noordik 2013 {published data only}
    1. Noordik E, Klink JJ, Geskus RB, Boer MR, Dijk FJ, Nieuwenhuijsen K. Effectiveness of an exposure‐based return‐to‐work program for workers on sick leave due to common mental disorders: a cluster‐randomized controlled trial. Scandinavian Journal of Work, Environment & Health 2013;39(2):144‐54. - PubMed
Norrefalk 2007 {published data only}
    1. Norrefalk JR, Linder J, Ekholm J, Borg K. A 6‐year follow‐up study of 122 patients attending a multiprofessional rehabilitation programme for persistent musculoskeletal‐related pain. International Journal of Rehabilitation Research 2007;30(1):9‐18. - PubMed
Ntsiea 2015 {published data only}
    1. Ntsiea MV, Aswegen H, Lord S, Olorunju S S. The effect of a workplace intervention programme on return to work after stroke: a randomised controlled trial. Clinical Rehabilitation 2015;29(7):663–73. - PubMed
Nystuen 2006 {published data only}
    1. Nystuen P, Hagen KB. Solution‐focused intervention for sick listed employees with psychological problems or muscle skeletal pain: a randomised controlled trial [ISRCTN39140363]. BMC Public Health 2006;6:69. - PMC - PubMed
Odeen 2013 {published data only}
    1. Odeen M, Ihlebaek C, Indahl A, Wormgoor ME, Lie SA, Eriksen HR. Effect of peer‐based low back pain information and reassurance at the workplace on sick leave: a cluster randomized trial. Journal of Occupational Rehabilitation 2013;23(2):209‐19. - PMC - PubMed
Okpaku 1997 {published data only}
    1. Okpaku S, Anderson KH, Sibulkin AE, Butler JS, Bickman L. The effectiveness of a multidisciplinary case management. Psychiatric Rehabilitation Journal 1997;20(3):34‐41.
Pedersen 2015 {published data only}
    1. Pedersen P, Søgaard HJ, Labriola M, Nohr EA, Jensen C. Effectiveness of psychoeducation in reducing sickness absence and improving mental health in individuals at risk of having a mental disorder: a randomised controlled trial. BMC Public Health 2015;15:763. [DOI: 10.1186/s12889-015-2087-5] - DOI - PMC - PubMed
Peters 1999 {published data only}
    1. Peters K, Carlson J. Worksite stress management with high‐risk maintenance workers: a controlled study. International Journal of Stress Management 1999;6(1):21‐44.
Petit 2014 {published data only}
    1. Petit A, Roche‐Leboucher G, Bontoux L, Dubus V, Ronzi Y, Roquelaure, Y, et al. Effectiveness of three treatment strategies on occupational limitations and quality of life for patients with non‐specific chronic low back pain: is a multidisciplinary approach the key feature to success? Study protocol for a randomized controlled trial. BMC Musculoskeletal Disorders 2014;15(1):131. - PMC - PubMed
Ponzer 2000 {published data only}
    1. Ponzer S, Molin U, Johansson SE, Bergman B, Törnkvist H. Psychosocial support in rehabilitation after orthopedic injuries. The Journal of Trauma 2000;48(2):273‐9. - PubMed
Poulsen 2014 {published data only}
    1. Poulsen OM, Aust B, Bjorner JB, Rugulies R, Hansen JV, Tverborgvik T, et al. Effect of the Danish return‐to‐work program on long‐term sickness absence: results from a randomized controlled trial in three municipalities. Scandinavian Journal of Work, Environment & Health 2014;40(1):47‐56. - PubMed
Raftery 2013 {published data only}
    1. Raftery MN, Murphy AW, O'Shea E, Newell J, McGuire BE. Effectiveness of a cognitive behavioural therapy‐based rehabilitation programme (Progressive Goal Attainment Program) for patients who are work‐disabled due to back pain: study protocol for a multicentre randomised controlled trial. Trials 2013;14:290. [DOI: 10.1186/1745-6215-14-290] - DOI - PMC - PubMed
Rebergen 2007 {published data only}
    1. Rebergen DS, Bruinvels DJ, Beek AJ, van MW. Design of a randomized controlled trial on the effects of counseling of mental health problems by occupational physicians on return to work: the CO‐OP‐study. BMC Public Health 2007;7:183. [DOI: 10.1186/1471-2458-7-183] - DOI - PMC - PubMed
Rebergen 2009a {published data only}
    1. Rebergen DS, Bruinvels DJ, Bezemer PD, Beek AJ, van MW. Guideline‐based care of common mental disorders by occupational physicians (CO‐OP study): a randomized controlled trial. Journal of Occupational and Environmental Medicine/American College of Occupational and Environmental Medicine 2009;51(3):305‐12. - PubMed
Rebergen 2009b {published data only}
    1. Rebergen DS, Bruinvels DJ, van‐Tulder MW, Beek AJ, van MW. Cost‐effectiveness of guideline‐based care for workers with mental health problems. Journal of Occupational and Environmental Medicine 2009;51(3):313‐22. - PubMed
Roche 2007 {published data only}
    1. Roche G, Ponthieux A, Parot SE, Jousset N, Bontoux L, Dubus V, et al. Comparison of a functional restoration program with active individual physical therapy for patients with chronic low back pain: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation 2007;88(10):1229‐35. - PubMed
Rolving 2014 {published data only}
    1. Rolving N, Oestergaard LG, Willert MV, Christensen FB, Blumensaat F, Bunger C, Nielsen CV. Description and design considerations of a randomized clinical trial investigating the effect of a multidisciplinary cognitive‐behavioural intervention for patients undergoing lumbar spinal fusion surgery. BMC Musculoskeletal Disorders 2014;15(1):62. - PMC - PubMed
Ross 2006 {published data only}
    1. Ross RH, Callas PW, Sargent JQ, Amick BC, Rooney T. Incorporating injured employee outcomes into physical and occupational therapists' practice: a controlled trial of the Worker‐Based Outcomes Assessment System. Journal of Occupational Rehabilitation 2006;16(4):607‐29. - PubMed
Rost 2004 {published data only}
    1. Rost K, Smith JL, Dickinson M. The effect of improving primary care depression management on employee absenteeism and productivity. A randomized trial. Medical Care 2004;42(12):1202‐10. - PMC - PubMed
Rupp 1996 {published data only}
    1. Rupp K, Wood M, Bell SH. Targeting people with severe disabilities for return‐to‐work: the Project NetWork demonstration experience. Journal of Vocational Rehabilitation 1996;7(1):63‐91.
Sacks 2008 {published data only}
    1. Sacks S, McKendrick K, Sacks JY, Banks S, Harle M. Enhanced outpatient treatment for co‐occurring disorders: main outcomes. Journal of Substance Abuse Treatment 2008;34(1):48‐60. - PubMed
Salazar 2010 {published data only}
    1. Salazar MK. Evaluation of a case management program. Summary and integration of findings. American Association of Occupational Health Nurses 2010;47(9):416‐23. - PubMed
Scheer 1995 {published data only}
    1. Scheer SJ, Radack KL, O'Brien DR Jr. Randomized controlled trials in industrial low back pain relating to return to work. Part 1. Acute interventions. Archives of Physical Medicine and Rehabilitation 1995;76(10):966‐73. - PubMed
Schene 2007 {published data only}
    1. Schene AH, Koeter MW, Kikkert MJ, Swinkels JA, McCrone P. Adjuvant occupational therapy for work‐related major depression works: randomized trial including economic evaluation. Psychological Medicine 2007;37(3):351‐62. - PubMed
Schultz 2008 {published data only}
    1. Schultz IZ, Crook J, Berkowitz J, Milner R, Meloche GR, Lewis ML. A prospective study of the effectiveness of early intervention with high‐risk back‐injured workers‐‐a pilot study. Journal of Occupational Rehabilitation 2008;18(2):140‐51. - PubMed
Shete 2012 {published data only}
    1. Shete KM, Suryawanshi P, Gandhi N. Management of low back pain in computer users: a multidisciplinary approach. Journal of Craniovertebral Junction and Spine 2012;3(1):7‐10. - PMC - PubMed
Shu‐Kei 2007 {published data only}
    1. Shu‐Kei C. Job coach model for occupational shoulder soft tissue injuries rehabilitation. Dissertation Abstracts International. Vol. 68, Hong Kong: Chinese University of Hong Kong, 2007.
Sjöström 2012 {published data only}
    1. Sjöström R, Asplund R, Alricsson M. Back to work: evaluation of a multidisciplinary rehabilitation program with emphasis on mental symptoms; A two‐year follow up. Journal of multidisciplinary healthcare 2012;5:145‐51. [DOI: 10.2147/JMDH.S32372] - DOI - PMC - PubMed
Skouen 2002 {published data only}
    1. Skouen JS, Grasdal AL, Haldorsen EM, Ursin H. Relative cost‐effectiveness of extensive and light multidisciplinary treatment programs versus treatment as usual for patients with chronic low back pain on long‐term sick leave: randomized controlled study. Spine 2002;27(9):901‐9. - PubMed
Skouen 2006 {published data only}
    1. Skouen JS, Grasdal A, Haldorsen EM. Return to work after comparing outpatient multidisciplinary treatment programs versus treatment in general practice for patients with chronic widespread pain. European Journal of Pain 2006;10(2):145‐52. - PubMed
Stapelfeldt 2015 {published data only}
    1. Stapelfeldt CM, Labriola M2 Jensen AB, Andersen NT, Momsen AM, Nielsen CV. Municipal return to work management in cancer survivors undergoing cancer treatment: a protocol on a controlled intervention study. BMC Public Health 2015;15:720. [DOI: 10.1186/s12889-015-2062-1] - DOI - PMC - PubMed
Steenstra 2003 {published data only}
    1. Steenstra IA, Anema JR, Bongers PM, de‐Vet HC, van MW. Cost effectiveness of a multi‐stage return to work program for workers on sick leave due to low back pain, design of a population based controlled trial [ISRCTN60233560]. BMC Musculoskeletal Disorders 2003;4:26. - PMC - PubMed
Steenstra 2006 {published data only}
    1. Steenstra IA, Anema JR, van‐Tulder MW, Bongers PM, de‐Vet HC, van MW. Economic evaluation of a multi‐stage return to work program for workers on sick‐leave due to low back pain. Journal of Occupational Rehabilitation 2006;16(4):557‐78. - PubMed
Steenstra 2007 {published data only}
    1. Steenstra IA, Anema JR, Bongers PM, Vet‐de HC, Knol DL, Loisel P, et al. Multidisciplinary rehabilitation for subacute low back pain: graded activity or workplace intervention or both? A randomized controlled trial. Spine 2007;32(3):299‐300. - PubMed
Steenstra 2009 {published data only}
    1. Steenstra IA, Knol DL, Bongers PM, Anema JR, Mechelen W, Vet HC. What works best for whom? An exploratory, subgroup analysis in a randomized, controlled trial on the effectiveness of a workplace intervention in low back pain patients on return to work. Spine 2009;34(12):1243‐9. - PubMed
Streibelt 2008 {published data only}
    1. Streibelt M, Blume C, Thren K, Müller FW. Economic evaluation of medically occupationally orientated rehabilitation in patients with musculoskeletal disorders‐‐a cost‐benefit analysis from the perspective of the German statutory pension insurance scheme [Ökonomische Evaluation einer medizinisch‐beruflich orientierten Maßnahme bei Patienten mit muskuloskeletalen Erkrankungen ‐ Eine Kosten‐Nutzen‐Analyse aus Rentenversicherungsperspektive]. Die Rehabilitation 2008;47(3):150‐7. - PubMed
Streibelt 2014 {published data only}
    1. Streibelt M, Bethge M. Effects of intensified work‐related multidisciplinary rehabilitation on occupational participation: a randomized‐controlled trial in patients with chronic musculoskeletal disorders. International Journal of Rehabilitation Research 2014;37(1):61‐6. - PubMed
Sundberg 2009 {published data only}
    1. Sundberg T, Petzold M, Wändell P, Rydén A, Falkenberg T. Exploring integrative medicine for back and neck pain ‐ a pragmatic randomised clinical pilot trial. BMC Complementary and Alternative Medicine 2009;9:33. [DOI: 10.1186/1472-6882-9-33] - DOI - PMC - PubMed
Svendsen 2014 {published data only}
    1. Svendsen SW, Christiansen DH, Haahr JP, Andrea LC, Frost P. Shoulder function and work disability after decompression surgery for subacromial impingement syndrome: a randomised controlled trial of physiotherapy exercises and occupational medical assistance. BMC Musculoskeletal Disorders 2014;15:215. [DOI: 10.1186/1471-2474-15-215] - DOI - PMC - PubMed
Tamminga 2013 {published data only}
    1. Tamminga SJ, Verbeek JH, Bos MM, Fons G, Kitzen JJ, Plaisier PW, et al. Effectiveness of a hospital‐based work support intervention for female cancer patients ‐ a multi‐centre randomised controlled trial. PLOS ONE 2013;8(5):e63271. - PMC - PubMed
Tamminga 2016 {published data only}
    1. Tamminga SJ, Hoving JL, Frings‐Dresen MH, Boer AG. Cancer@Work — a nurse‐led, stepped‐care,e‐health intervention to enhance the return to work of patients with cancer: study protocol for a randomized controlled trial. Trials 2016;17:1. - PMC - PubMed
Thunnissen 2008 {published data only}
    1. Thunnissen M, Duivenvoorden H, Busschbach J, Hakkaart‐van Roijen L, Tilburg W, Verheul R, et al. A randomized clinical trial on the effectiveness of a reintegration training program versus booster sessions after short‐term inpatient psychotherapy. Journal of Personality Disorders 2008;22(5):483‐95. - PubMed
Van Beurden 2012 {published data only}
    1. Beurden KM, Vermeulen SJ, Anema JR, Beek AJ. A participatory return‐to‐work program for temporary agency workers and unemployed workers sick‐listed due to musculoskeletal disorders: a process evaluation alongside a randomized controlled trial. Journal of Occupational Rehabilitation 2012;22(1):127‐40. - PMC - PubMed
Van Beurden 2015 {published data only}
    1. Beurden KM, Klink JJ, Brouwers EP, Joosen MC, Mathijssen JJ, Terluin B, et al. Effect of an intervention to enhance guideline adherence of occupational physicians on return‐to‐work self‐efficacy in workers sick‐listed with common mental disorders. BMC Public Health 2015;15:796. [DOI: 10.1186/s12889-015-2125-3] - DOI - PMC - PubMed
Van der Klink 2003 {published data only}
    1. Klink JJ, Blonk RW, Schene AH, van‐Dijk FJ. Reducing long term sickness absence by an activating intervention in adjustment disorders: a cluster randomised controlled design. Occupational and Environmental Medicine 2003;60(6):429‐37. - PMC - PubMed
Van Oostrom 2008 {published data only}
    1. Oostrom SH, Anema JR, Terluin B, Vet HC, Knol DL, van MW. Cost‐effectiveness of a workplace intervention for sick‐listed employees with common mental disorders: design of a randomized controlled trial. BMC Public Health 2008;8:12. [DOI: 10.1186/1471-2458-8-12] - DOI - PMC - PubMed
Van Oostrom 2010 {published data only}
    1. Oostrom SH, Mechelen W, Terluin B, Vet HC, Knol DL, Anema JR. A workplace intervention for sick‐listed employees with distress: results of a randomised controlled trial. Occupational and Environmental Medicine 2010;67(9):596‐602. - PubMed
Varekamp 2011 {published data only}
    1. Varekamp I, Verbeek JH, Boer A, Dijk FJ. Effect of job maintenance training program for employees with chronic disease ‐ a randomized controlled trial on self‐efficacy, job satisfaction, and fatigue. Scandinavian Journal of Work, Environment & Health 2011;37(4):288‐97. - PubMed
Vermeulen 2010 {published data only}
    1. Vermeulen SJ, Anema JR, Schellart AJ, van MW, Beek AJ. Cost‐effectiveness of a participatory return‐to‐work intervention for temporary agency workers and unemployed workers sick‐listed due to musculoskeletal disorders: design of a randomised controlled trial [Protocol]. BMC Musculoskeletal Disorders 2010;11:60. [DOI: 10.1186/1471-2474-11-60] - DOI - PMC - PubMed
Vermeulen 2011 {published data only}
    1. Vermeulen SJ, Anema JR, Schellart AJ, Knol DL, Mechelen W, Beek AJ. A participatory return‐to‐work intervention for temporary agency workers and unemployed workers sick‐listed due to musculoskeletal disorders: results of a randomized controlled trial. Journal of Occupational Rehabilitation 2011;21(3):313‐24. - PMC - PubMed
Vidor 2014 {published data only}
    1. Vidor C, Leroyer A, Christophe V, Seillier M, Foncel J, Maele J, et al. Decrease social inequalities return‐to‐work: development and design of a randomised controlled trial among women with breast cancer. BMC Cancer 2014;14:267. [DOI: 10.1186/1471-2407-14-267] - DOI - PMC - PubMed
Vissers 2008 {published data only}
    1. ISRCTN31632033. The efficacy and predicting variables of a multidisciplinary disability resolution (MDR) program for CFS patients receiving long term disability benefits from income protection insurers. www.isrctn.com/ISRCTN31632033 (first received 4 April 2006).
Vlasveld 2013 {published data only}
    1. Vlasveld MC, Feltz‐Cornelis CM, Ader HJ, Anema JR, Hoedeman R, Mechelen W, et al. Collaborative care for sick‐listed workers with major depressive disorder: a randomised controlled trial from the Netherlands Depression Initiative aimed at return to work and depressive symptoms. Occupational and Environmental Medicine 2013;70(4):223‐30. - PubMed
Vonk Noordegraaf 2014 {published data only}
    1. Vonk Noordegraaf A, Anema JR, Mechelen W, Knol DL, Baal WM, Kesteren PJ, et al. A personalised eHealth programme reduces the duration until return to work after gynaecological surgery: results of a multicentre randomised trial. BJOG: An International Journal of Obstetrics and Gynaecology 2014;121(9):1127‐35; discussion 36. - PubMed
Wang 2007 {published data only}
    1. Wang PS, Simon GE, Avorn J, Azocar F, Ludman EJ, McCulloch J, et al. Telephone screening, outreach, and care management for depressed workers and impact on clinical and work productivity outcomes: a randomized controlled trial. JAMA 2007;298(12):1401‐11. - PMC - PubMed
Westman 2010 {published data only}
    1. Westman A, Linton SJ, Ohrvik J, Wahlén P, Theorell T, Leppert J. Controlled 3‐year follow‐up of a multidisciplinary pain rehabilitation program in primary health care. Disability and Rehabilitation 2010;32(4):307‐16. - PubMed
Whitehurst 2007 {published data only}
    1. Whitehurst DG, Lewis M, Yao GL, Bryan S, Raftery JP, Mullis R, et al. A brief pain management program compared with physical therapy for low back pain: results from an economic analysis alongside a randomized clinical trial. Arthritis & Rheumatology 2007;57(3):466‐73. - PubMed
Willert 2011 {published data only}
    1. Willert MV, Thulstrup AM, Bonde JP. Effects of a stress management intervention on absenteeism and return to work‐results from a randomized wait‐list controlled trial. Scandinavian Journal of Work, Environment & Health 2011;37(3):186‐95. - PubMed
Yassi 1995 {published data only}
    1. Yassi A, Tate R, Cooper JE, Snow C, Vallentyne S, Khokhar JB. Early intervention for back‐injured nurses at a large Canadian tertiary care hospital: an evaluation of the effectiveness and cost benefits of a two‐year pilot project. Occupational Medicine 1995;45(4):209‐14. - PubMed
Zaman 2016 {published data only}
    1. Zaman AG, Tytgat KM, Klinkenbijl JH, Frings‐Dresen MH, Boer AG. Design of a multicentre randomized controlled trial to evaluate the effectiveness of a tailored clinical support intervention to enhance return to work for gastrointestinal cancer patients. BMC Cancer 2016;16:303. [DOI: 10.1186/s12885-016-2334] - DOI - PMC - PubMed
Zhang 1994 {published data only}
    1. Zhang M, Yan H, Phillips MR. Community‐based psychiatric rehabilitation in Shanghai. Facilities, services, outcome, and culture‐specific characteristics. The British Journal of Psychiatry. Supplement 1994;165(24):70‐9. - PubMed
Østerås 2009 {published data only}
    1. Østerås N, Gulbrandsen P, Benth JS, Hofoss D, Brage S. Implementing structured functional assessments in general practice for persons with long‐term sick leave: a cluster randomised controlled trial. BMC Family Practice 2009;10:31. [DOI: 10.1186/1471-2296-10-31] - DOI - PMC - PubMed

References to studies awaiting assessment

Norén 2015 {published data only}
    1. Norén AM, Bengtner J, Landström S, Sjöberg E. Rehabilitation coordination for return to work, as extended role for health professionals ‐ results from a randomized controlled trial. Health Professionals in Rheumatology Abstracts 2015;SAT0646‐HPR:1337.

Additional references

Akl 2012
    1. Akl EA, Sun X, Busse JW, Johnston BC, Briel M, Mulla S, et al. Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. Journal of Clinical Epidemiology 2012;65(3):262‐7. - PubMed
Arends 2012
    1. Arends I, Bruinvels DJ, Rebergen DS, Nieuwenhuijsen K, Madan I, Neumeyer‐Gromen A, et al. Interventions to facilitate return to work in adults with adjustment disorders. Cochrane Database of Systematic Reviews 2012, Issue 12. [DOI: 10.1002/14651858.CD006389.pub2] - DOI - PMC - PubMed
Berchtold 2006
    1. Berchtold P, Hess K. Evidenz für Managed Care: Europäische Literaturanalyse unter besonderer Berücksichtigung der Schweiz: Wirkung von Versorgungssteuerung auf Qualität und Kosteneffektivität. Vol. Arbeitsdokument des Obsan 16, Neuchâtel: Schweizerisches Gesundheitsobservatorium, 2006.
Campbell 2001
    1. Campbell MK, Mollison J, Grimshaw JM. Cluster trials in implementation research: estimation of intracluster correlation coefficients and sample size. Statistics in Medicine 2001;20(3):391‐9. - PubMed
Canadian Human Rights Commission 2007
    1. Canadian Human Rights Commission. A Guide for Managing the Return to Work. Minister of Public Works and Government Services 2007. www.chrc‐ccdp.ca/eng/content/guide‐managing‐return‐work (accessed 10 October 2014).
Chamberlain 1991
    1. Chamberlain R, Rapp CA. A decade of case management: a methodological review of outcome research. Community Mental Health Journal 1991;27(3):171‐88. - PubMed
Clayton 2011
    1. Clayton S, Bambra C, Gosling R, Povall S, Misso K, Whitehead M. Assembling the evidence jigsaw: insights from a systematic review of UK studies of individual‐focused return to work initiatives for disabled and long‐term ill people. BMC Public Health 2011;11:170. - PMC - PubMed
Craig 2013
    1. Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. International Journal of Nursing Studies 2013;50(5):587‐92. - PubMed
Department for Work and Pensions 2013
    1. Department for Work and Pensions. Working for a healthier tomorrow: work and health in Britain. July 2013. Available from www.gov.uk/government/publications/working‐for‐a‐healthier‐tomorrow‐work....
Henderson 2005
    1. Henderson M, Glozier N, Holland Elliott K. Long term sickness absence. BMJ 2005;330(7495):802‐3. - PMC - PubMed
Higgins 2011
    1. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane‐handbook.org.
Hoefsmit 2012
    1. Hoefsmit N, Houkes I, Nijhuis FJ. Intervention characteristics that facilitate return to work after sickness absence: a systematic literature review. Journal of Occupational Rehabilitation 2012;22(4):462‐77. - PMC - PubMed
Hoffmann 2014
    1. Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ 2014;348:g1687. [DOI: 10.1136/bmj.g1687] - DOI - PubMed
Hofmarcher 2007
    1. Hofmarcher MM, Oxley H, Rusticelli E. Improved health system performance through better care coordination. December 2007. OECD Health Working Papers, No. 30, OECD Publishing, Paris. Available from www.oecd‐ilibrary.org/social‐issues‐migration‐health/improved‐health‐system‐perfo....
IWH 2007
    1. Institute for Work & Health. Seven 'principles' for successful return to work. www.iwh.on.ca/seven‐principles‐for‐rtw (accessed 8 December 2014).
Johnston 2010
    1. Johnston BC, Thorlund K, Schunemann HJ, Xie F, Murad MH, Montori VM, et al. Improving the interpretation of quality of life evidence in meta‐analyses: the application of minimal important difference units. Health and Quality of Life Outcomes 2010;8:116. [DOI: 10.1186/1477-7525-8-116] - DOI - PMC - PubMed
Kuoppala 2008
    1. Kuoppala J, Lamminpää A. Rehabilitation and work ability: a systematic literature review. Journal of Rehabilitation Medicine 2008;40(10):796–804. - PubMed
Marchand 2015
    1. Marchand GH, Myhre K, Leivseth G, Sandvik L, Lau B, Bautz‐Holter E, et al. Change in pain, disability and influence of fear‐avoidance in a work‐focused intervention on neck and back pain: a randomized controlled trial. BMC Musculoskeletal Disorders 2015;16(1):94. - PMC - PubMed
Moher 2009
    1. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta‐analyses: the PRISMA statement. Journal of Clinical Epidemiology 2009;62(10):1006‐12. - PubMed
NICE 2009
    1. National Institute for Health and Care Excellence. Managing long‐term sickness and incapacity for work. NICE guidelines [PH19]. 2009 March. Available from www.nice.org.uk/guidance/PH19.
Nieuwenhuijsen 2014
    1. Nieuwenhuijsen K, Faber B, Verbeek JH, Neumeyer‐Gromen A, Hees HL, Verhoeven AC, et al. Interventions to improve return to work in depressed people. Cochrane Database of Systematic Reviews 2014, Issue 12. [DOI: 10.1002/14651858.CD006237.pub3] - DOI - PMC - PubMed
OECD 2003
    1. Organisation for Economic Cooperation and Development (OECD). Transforming disability into ability: policies to promote work and income security for disabled people. 2003 February. OECD Publishing, Paris. Available from www.oecd‐ilibrary.org/content/book/9789264158245‐en. [DOI: ]
OECD 2010
    1. Organisation for Economic Cooperation and Development (OECD). Sickness, Disability and Work: Breaking the Barriers: A Synthesis of Findings across OECD Countries. 2010 November. OECD Publishing, Paris. Available from www.oecd‐ilibrary.org/social‐issues‐migration‐health/sickness‐disability‐and‐work.... [DOI: ]
OECD 2014 a
    1. Organisation for Economic Cooperation and Development (OECD). Economic Policy Reforms 2014: Going for Growth Interim Report. 2014 February. OECD Publishing, Paris. Available from www.oecd‐ilibrary.org/economics/economic‐policy‐reforms‐2014_growth‐2014‐en. [DOI: ]
OECD 2014 b
    1. Organisation for Economic Cooperation and Development (OECD). Making Mental Health Count. The Social and Economic Costs of Neglecting Mental Health Care. July 2014. OECD Health Policy Studies, OECD Publishing, Paris. Available from www.oecd.org/els/health‐systems/Focus‐on‐Health‐Making‐Mental‐Health‐Cou....
Palmer 2012
    1. Palmer KT, Harris EC, Linaker C, Barker M, Lawrence W, Cooper C, et al. Effectiveness of community‐ and workplace‐based interventions to manage musculoskeletal‐related sickness absence and job loss: a systematic review. Rheumatology 2012;51(2):230‐42. - PMC - PubMed
R 2015 [Computer program]
    1. R Core Team. R: A language and environment for statistical computing. Version 3.2.0. Vienna: R Foundation for Statistical Computing, 2015.
RevMan 2014 [Computer program]
    1. The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
Shaw 2001
    1. Shaw WS, Feuerstein M, Lincoln AE, Miller VI, Wood PM. Case management services for work related upper extremity disorders. Integrating workplace accommodation and problem solving. AAOHN Journal 2001;49(8):378‐89. - PubMed
Thorlund 2011
    1. Thorlund K, Walter SD, Johnston BC, Furukawa TA, Guyatt GH. Pooling health‐related quality of life outcomes in meta‐analysis ‐ a tutorial and review of methods for enhancing interpretability. Research Synthesis Methods 2011;2(3):188‐203. - PubMed
Thornicroft 1991
    1. Thornicroft G. The concept of case management for long term mental illness. International Review of Psychiatry 1991;3(1):125‐32.
Van der Feltz‐Cornelis 1996
    1. Feltz‐Cornelis CM, Wijkel D, Verhaak PF, Collijn DH, Huyse FJ, Dyck R. Psychiatric consultation for somatizing patients in the family practice setting: a feasibility study. The International Journal of Psychiatry in Medicine 1996;26(2):223‐39. - PubMed
Van Vilsteren 2015
    1. Vilsteren M, Oostrom SH, Vet HCW, Franche RL, Boot CRL, Anema JR. Workplace interventions to prevent work disability in workers on sick leave. Cochrane Database of Systematic Reviews 2015, Issue 10. [DOI: 10.1002/14651858.CD006955.pub3] - DOI - PMC - PubMed
Verbeek 2012
    1. Verbeek J, Ruotsalainen J, Hoving JL. Synthesizing study results in a systematic review. Scandinavian Journal of Work Environment & Health 2012;38(3):282‐90. - PubMed
Waddell 2006
    1. Waddell G, Burton AK. Is work good for your health & well‐being? Commissioned by the Department for Work and Pensions. Published by TSO (The Stationery Office). 2006. Available from www.gov.uk/government/uploads/system/uploads/attachment_data/file/214326....

References to other published versions of this review

Schandelmaier 2012
    1. Schandelmaier S, Ebrahim S, Burkhardt SC, Boer WE, Zumbrunn T, Guyatt GH, et al. Return to work coordination programmes for work disability: a meta‐analysis of randomised controlled trials. PLOS ONE 2012;7(11):e49760. - PMC - PubMed
Vogel 2015
    1. Vogel N, Schandelmaier S, Zumbrunn T, Ebrahim S, Boer WEL, Mousavi SM, et al. Return to work coordination programmes for improving return to work in workers on sick leave. Cochrane Database of Systematic Reviews 2015, Issue 3. [DOI: 10.1002/14651858.CD011618] - DOI - PMC - PubMed

MeSH terms