[Multimodal imaging in primary intraocular lymphoma]

Abstract

Introduction: Vitreoretinal lymphoma is a serious disease with highly varied clinical presentations. The goal of this work is to identify the various presentations (clinical, imaging) in order to improve screening for this disease.

Materials and method: We collected data of patients followed on our service for vitreoretinal lymphoma. The fundus exam, autofluorescence and angiography data were classified in order to identify signs, which might lead to earlier diagnosis of lymphoma.

Results: The diagnosis of vitreoretinal lymphoma was confirmed by vitrectomy or cerebral biopsy for 12 patients (8 women and 4 men). Three clinical presentations were identified: no retinal involvement (2 patients), retinal infiltrate (4 patients) or acute retinal necrosis (3 patients). One patient had no imaging (deceased before it could be obtained), and two patients had uninterpretable imaging.

Conclusion: Vitreoretinal lymphoma remains a rare and under-diagnosed disease. The prognosis is related to early diagnosis. Multimodal imaging can help to diagnose early vitreoretinal lymphoma in some cases.

Keywords: Fond d’œil; Imagerie rétinienne; Infiltrat rétinien; Lymphome vitréorétinien; Nécrose rétinienne; Ocular fundus; Retinal imaging; Retinal infiltrate; Retinal necrosis; Vitreoretinal lymphoma.