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. 2016 Dec;53(4):328-333.
doi: 10.5152/npa.2016.11327. Epub 2016 Dec 1.

Symptomatic Remission Determines Functional Improvement and Quality of Life in Schizophrenia

Mehmet Hanifi Kokaçya  1 , Osman Virit  2 , Ümit Sertan Çöpoğlu  2 , Haluk Savaş  2 , Mustafa Ari  1 , Bülent Bahçeci  3
Affiliations

Symptomatic Remission Determines Functional Improvement and Quality of Life in Schizophrenia

Mehmet Hanifi Kokaçya et al. Noro Psikiyatr Ars. 2016 Dec.

Abstract

Introduction: Schizophrenia is a chronic illness that negatively affects the quality of life and psychosocial functions. Defined criteria to assess remission in schizophrenia are considered to be useful in the long-term follow-up of patients and in discriminating diagnostic factors. This study investigated the quality of life and functionality in schizophrenia patients in symptomatic remission (R-Sch) and not in remission (Non-R-Sch).

Methods: Sociodemographic data were collected for 40 R-Sch and 40 Non-R-Sch patients, and the following scales were administered: the Clinical Global Impression-Severity (CGI-S) Scale; Positive and Negative Syndrome Scale (PANSS), World Health Organization Quality of Life Questionnaire-Short Form, Turkish Version (WHOQOL-BREF-TR), Quality of Life Scale for Schizophrenia Patients (QLS), and Global Assessment of Functioning Scale (GAF).

Results: The total and all subscale scores of PANSS and the CGI-S score were significantly lower in the R-Sch group than in the Non-R-Sch group, whereas the GAF scores and all subscales of QLS and WHOQOL-BREF-TR were significantly higher.

Conclusion: This study demonstrates that improvement in symptoms in schizophrenia patients improves quality and functionality in all areas of life, suggesting that an improvement in symptoms is the most important determinant of functional recovery in the treatment of schizophrenia.

Keywords: Schizophrenia; quality of life; symptomatic remission.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

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