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. 2017 May:99:105-108.
doi: 10.1016/j.maturitas.2017.02.015. Epub 2017 Feb 28.

Sleep patterns, sleep disorders and mammographic density in spanish women: The DDM-Spain/Var-DDM study

Ana María Pedraza-Flechas  1 , Virginia Lope  2 , Pilar Moreo  3 , Nieves Ascunce  4 , Josefa Miranda-García  5 , Carmen Vidal  6 , Carmen Sánchez-Contador  7 , Carmen Santamariña  8 , Carmen Pedraz-Pingarrón  9 , Rafael Llobet  10 , Nuria Aragonés  2 , Dolores Salas-Trejo  5 , Marina Pollán  2 , Beatriz Pérez-Gómez  11 ; DDM/Var-DDM-Spain
Affiliations
Free article

Sleep patterns, sleep disorders and mammographic density in spanish women: The DDM-Spain/Var-DDM study

Ana María Pedraza-Flechas et al. Maturitas. 2017 May.
Free article

Abstract

We explored the relationship between sleep patterns and sleep disorders and mammographic density (MD), a marker of breast cancer risk. Participants in the DDM-Spain/var-DDM study, which included 2878 middle-aged Spanish women, were interviewed via telephone and asked questions on sleep characteristics. Two radiologists assessed MD in their left craneo-caudal mammogram, assisted by a validated semiautomatic-computer tool (DM-scan). We used log-transformed percentage MD as the dependent variable and fitted mixed linear regression models, including known confounding variables. Our results showed that neither sleeping patterns nor sleep disorders were associated with MD. However, women with frequent changes in their bedtime due to anxiety or depression had higher MD (eβ:1.53;95%CI:1.04-2.26).

Keywords: Breast cancer; Mammographic density; Sleep disorders; Sleep patterns.

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