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. 2017 Jul;33(7):492-495.
doi: 10.1016/j.pt.2017.03.002. Epub 2017 Mar 30.

Malaria Eradication and the Hidden Parasite Reservoir

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Malaria Eradication and the Hidden Parasite Reservoir

Miles B Markus. Trends Parasitol. 2017 Jul.

Abstract

Accumulation of erythrocytic parasites in bone marrow and the spleen has been reported in cases of Plasmodium vivax malaria. If this occurs commonly, these stages represent a possible source of early, relapse-like homologous recurrences. Moreover, they might hinder the elimination of malaria from human populations. Pertinent research suggestions have been made.

Keywords: Plasmodium cynomolgi; Plasmodium vivax; elimination; eradication; hypnozoite; relapse.

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