Malaria Eradication and the Hidden Parasite Reservoir
- PMID: 28366603
- DOI: 10.1016/j.pt.2017.03.002
Malaria Eradication and the Hidden Parasite Reservoir
Abstract
Accumulation of erythrocytic parasites in bone marrow and the spleen has been reported in cases of Plasmodium vivax malaria. If this occurs commonly, these stages represent a possible source of early, relapse-like homologous recurrences. Moreover, they might hinder the elimination of malaria from human populations. Pertinent research suggestions have been made.
Keywords: Plasmodium cynomolgi; Plasmodium vivax; elimination; eradication; hypnozoite; relapse.
Copyright © 2017 Elsevier Ltd. All rights reserved.
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