Genetic screens: CRISPR-based mapping of genetic interactions

Affiliations

Comment

Ross Cloney. Nat Rev Genet. 2017 May.

. 2017 May;18(5):272-273.

doi: 10.1038/nrg.2017.25. Epub 2017 Apr 3.

No abstract available

Comment on

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.
Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Han K, et al. Nat Biotechnol. 2017 May;35(5):463-474. doi: 10.1038/nbt.3834. Epub 2017 Mar 20. Nat Biotechnol. 2017. PMID: 28319085 Free PMC article.
Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.
Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, Lewis NE, Chang AN, Kreisberg JF, Krogan N, Qi L, Ideker T, Mali P. Shen JP, et al. Nat Methods. 2017 Jun;14(6):573-576. doi: 10.1038/nmeth.4225. Epub 2017 Mar 20. Nat Methods. 2017. PMID: 28319113 Free PMC article.