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Case Reports
. 2017 Jan;7(1):e59-e63.
doi: 10.1055/s-0037-1599124.

Perinatal and Neonatal Outcomes of Triplet Gestations Based on Chorionicity

Maureen Downing  1 , Suela Sulo  2 , Barbara V Parilla  1
Affiliations
Case Reports

Perinatal and Neonatal Outcomes of Triplet Gestations Based on Chorionicity

Maureen Downing et al. AJP Rep. 2017 Jan.

Abstract

Objective To compare perinatal and neonatal outcomes of dichorionic (DC) and monochorionic (MC) with trichorionic (TC) triplet gestations. Methods A retrospective cohort study of DC + MC versus TC triplet gestations delivered at a tertiary care hospital from 2009 to 2015. The results include 42 sets of triplets (TC, n = 26; DC + MC, n = 16). Maternal demographics and pregnancy data were compared. Neonatal outcomes were assessed using composite morbidity and mortality. Results Maternal baseline characteristics including age, mode of conception, race, parity, body mass index, and previous preterm delivery were statistically comparable. Comparison of prenatal management and complications yielded no significant differences in terms of presence of shortened cervix, cerclage placement, use of tocolytics, intrauterine growth restriction, premature rupture of membranes, pregnancy-induced hypertension, or gestational diabetes. However, evaluation of composite morbidity and mortality (RDS, IVH, NEC, IUGR, and death) illustrated that all infants born from DC + MC triplet gestations suffered some morbidity or mortality compared with TC pregnancies (p < 0.01). Conclusion DC + MC triplet gestations are at an increased risk of neonatal morbidity and mortality compared with TC triplet gestations.

Keywords: diamniotic; dichorionic triplets; monochorionic triplets; monochorionic twin pair in triplet gestation; triplet gestation outcomes; triplet outcomes based on chorionicity.

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Conflict of interest statement

Financial Disclosure The authors have no conflicts of interest to report. Presented as a poster at the Annual Meeting of the American College of Obstetricians and Gynecologists, May 14–17, 2016, Washington, DC, United States.

References

    1. Martin J A, Hamilton B E, Osterman M J. Three decades of twin births in the United States, 1980-2009. NCHS Data Brief. 2012;(80):1–8. - PubMed
    1. et al.ACOG Practice Bulletin No. 144: Multifetal gestations: twin, triplet, and higher-order multifetal pregnancies. Obstet Gynecol. 2014;123(05):1118–1132. - PubMed
    1. Practice Committee of American Society for Reproductive Medicine. Multiple gestation associated with infertility therapy: an American Society for Reproductive Medicine Practice Committee opinion Fertil Steril 20129704825–834. - PubMed
    1. Parilla B V, Goldman B, Jasulaitis S, Sulo S, Beltsos A. Risk factors associated with dichorionic triplet gestations. Open J Obstet Gynecol. 2015;5(13):740–745.
    1. Ortibus E, Lopriore E, Deprest J et al.The pregnancy and long-term neurodevelopmental outcome of monochorionic diamniotic twin gestations: a multicenter prospective cohort study from the first trimester onward. Am J Obstet Gynecol. 2009;200(05):4940–4.94E10. - PubMed

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